Screening, Modelling and Optimization of Soluble Medical Glasses & Ceramics

可溶医用玻璃的筛选、建模和优化

• 批准号: RGPIN-2022-03371
• 负责人: Boyd, Daniel
• 金额: $ 2.84万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=750703
• 关键词: Screening; Modelling; Optimization; Soluble; Medical

Advanced materials are essential to economic security and human health. However, the timeframes to discover, develop and deploy new materials is typically on the order of 15-20 years. Governments recognise that accelerating the pace of discovery and deployment of advanced material systems will be crucial to achieving global competitiveness in the 21st century. This research program is focused on discovering, developing, and commercializing new materials technologies faster and at a fraction of the cost associated with traditional materials development. The focus of this research is on degradable materials that can be used as, or as part of, medical devices, pharmaceuticals, or industrial materials/components. In order to achieve this goal, this research program will use, explore, and discover material chemistries that have not been given adequate attention in the scientific literature yet hold significant promise for innovation in materials science. The research program will use advanced modelling to design and test these innovative new materials in a manner that allows materials researchers to predict the performance of a range of materials across industries. This predictive power will shorten the time it takes to develop new materials for commercial use, and also provide the scientific community with much needed data on the composition, structure, and properties of soluble materials. The principal investigator for this work has already demonstrated an ability to rapidly discover, design and deploy unique materials, and his work has generated new manufacturing facilities, jobs, and record setting investments for the Atlantic provinces. Now the researchers are turning their attention to soluble materials that can be placed in the body, and while degrading, release elements that encourage the body to heal itself. Once the material has completed its function, it will be safely eliminated from the body, allowing return to normal function. As a result, and based on the track record of the researcher, this program will lead to breakthrough materials science data that can be harnessed to develop new treatments, new technologies, new companies, and new jobs in Canada. The program will also train the next generation of scientists and engineers, from a diverse set of backgrounds, to advance their breakthrough research into commercial use. Consequently, this program will drive economic, social and health benefits for Canadians. This research is valuable and useful for materials scientists, medical device engineers, materials development companies, medical device companies, chemical companies, and will provide industry, academia, and governments with radical materials innovation to secure global competitiveness in the 21st century.

先进材料对经济安全和人类健康至关重要。然而，发现、开发和部署新材料的时间通常为15-20年。各国政府认识到，加快发现和部署先进材料系统的步伐，对于在21世纪实现全球竞争力至关重要。该研究计划的重点是更快地发现，开发和商业化新材料技术，并且成本仅为传统材料开发的一小部分。本研究的重点是可降解材料，可用作医疗器械，药品或工业材料/组件或其一部分。为了实现这一目标，该研究计划将使用，探索和发现在科学文献中尚未得到足够关注的材料化学，但对材料科学的创新具有重大的希望。该研究计划将使用先进的建模来设计和测试这些创新的新材料，使材料研究人员能够预测跨行业的一系列材料的性能。这种预测能力将缩短开发用于商业用途的新材料所需的时间，并为科学界提供有关可溶性材料的组成，结构和性质的急需数据。这项工作的首席研究员已经证明了快速发现，设计和部署独特材料的能力，他的工作为大西洋省份创造了新的制造设施，就业机会和创纪录的投资。现在，研究人员将注意力转向了可以放置在体内的可溶性材料，在降解的同时，释放出鼓励身体自愈的元素。一旦材料完成其功能，它将被安全地从体内清除，使其恢复正常功能。因此，根据研究人员的跟踪记录，该计划将导致突破性的材料科学数据，可以利用这些数据在加拿大开发新的治疗方法，新技术，新公司和新的就业机会。该计划还将培训来自不同背景的下一代科学家和工程师，以推动他们的突破性研究进入商业用途。因此，该计划将推动加拿大人的经济，社会和健康福利。这项研究对材料科学家、医疗器械工程师、材料开发公司、医疗器械公司、化学公司都是有价值和有用的，并将为工业界、学术界和政府提供彻底的材料创新，以确保世纪的全球竞争力。