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Investigating the role of neuronal STI1 co-chaperone in facilitating in vivo a-synuclein toxicity

Investigating the role of neuronal STI1 co-chaperone in facilitating in vivo a-synuclein toxicity
研究神经元 STI1 共伴侣在促进体内 α-突触核蛋白毒性中的作用
批准号:
475875
负责人:
Novikov Vladislav
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-11-01 至 2025-11-01

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中文摘要
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英文摘要
a-synuclein (aS) is an aggregation prone protein found to be misfolded in Parkinson's disease. A special class of molecules known as chaperones and co-chaperones normally work in unison to properly fold proteins and avoid their aggregation. However, in ne
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Impact of Modulating STI1 Expression Levels on TDP-43 Induced Pathology in a Mouse Model of ALS
  • 批准号:
    429003
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2019
  • 负责人:
    Novikov Vladislav
  • 依托单位:
海外基金