Improve genomic testing tools for fertility traits in beef cattle

生育率是牛肉产业生产力和盈利能力的关键驱动因素；然而，一个重大的行业挑战是生育率低，以及在偏远的澳大利亚测量生育率的难度和费用。通过整合多个组学数据集和记录在肉牛身上的5万种生育力表型，该项目将确定序列变异，包括结构变异，这些变异是牛生育力遗传变异的基础。我们的行业合作伙伴每年对数十万头牛进行基因分型，将生产新的基因型阵列和新的低成本测序方法，包括这些变异，使选择有可能使牛群繁殖率提高4%，每年为农民带来4000万美元的回报。

Fertility is a key driver of productivity and profitability for beef industry; however, a substantial industry challenge is poor fertility and the difficulty and expense of measuring fertility in remote Australia. By integrating multiple omics datasets and fifty thousand fertility phenotypes recorded on beef cattle, the project will identify sequence variation, including structural variants, that underpin genetic variation in cattle fertility. Our industry partner, which genotypes hundreds of thousands of cattle a year, will produce new genotype arrays and novel low-cost sequencing approaches including these variants, enabling selection that could potentially increase herd reproductive rate by 4%, returning $40M per annum to the farmers.