Improve genomic testing tools for fertility traits in beef cattle

改进肉牛生育性状的基因组测试工具

• 批准号: IE230100263
• 负责人: Dr Loan Nguyen
• 金额: $ 33.31万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Industry Fellowships
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/IE230100263
• 关键词: Improve; genomic; testing; tools; fertility

Fertility is a key driver of productivity and profitability for beef industry; however, a substantial industry challenge is poor fertility and the difficulty and expense of measuring fertility in remote Australia. By integrating multiple omics datasets and fifty thousand fertility phenotypes recorded on beef cattle, the project will identify sequence variation, including structural variants, that underpin genetic variation in cattle fertility. Our industry partner, which genotypes hundreds of thousands of cattle a year, will produce new genotype arrays and novel low-cost sequencing approaches including these variants, enabling selection that could potentially increase herd reproductive rate by 4%, returning $40M per annum to the farmers.

生育率是牛肉行业生产力和盈利能力的关键驱动力;然而，一个重大的行业挑战是生育率低，以及在澳大利亚偏远地区测量生育率的困难和费用。通过整合多个组学数据集和肉牛上记录的5万个生育表型，该项目将确定序列变异，包括结构变异，这些变异是牛生育力遗传变异的基础。我们的行业合作伙伴每年对数十万头牛进行基因分型，将生产新的基因型阵列和新的低成本测序方法，包括这些变体，从而实现选择，可能将牛群繁殖率提高4%，每年为农民带来4000万美元的回报。