Exploring APOL1 genetic risk and family perspectives on clinical genetic testing in children of African ancestry with nephrotic syndrome in Ontario

探讨安大略省非洲血统肾病综合征儿童的 APOL1 遗传风险和家庭视角对临床基因检测的影响

• 批准号: 486524
• 负责人: Ahmed Ranie
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486524&lang=en
• 关键词: Focus Groups; Genetic Epidemiology; Genetics; Gwas; Nephrology; Pediatrics

Chronic kidney disease affects 14% of people in Sub-Saharan Africa and a common cause is nephrotic syndrome in children and adults. In nephrotic syndrome, the kidneys leak proteins in the urine and cause swelling of the body, breathing problems, blood clo

慢性肾脏疾病影响撒哈拉以南非洲14%的人口，儿童和成人的常见病因是肾病综合征。在肾病综合征中，肾脏会在尿液中漏出蛋白质，导致身体肿胀、呼吸困难和血凝