Next-generation mRNA manufacturing and analysis technologies

下一代 mRNA 制造和分析技术

• 批准号: IE230100169
• 负责人: Dr Hareth Al-Wassiti
• 金额: $ 31.9万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Industry Fellowships
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/IE230100169
• 关键词: Next; generation; mRNA; manufacturing; analysis

Developing innovations in RNA manufacturing and technology. The project aims to develop cutting-edge manufacturing and analysis technologies by optimising Self-amplifying (SAM) RNA production towards low impurities, creating reliable purification technologies, and filling critical gaps in RNA analysis. The project expects to yield significantly cheaper, higher-quality RNA products and develop novel methods in RNA analysis. The outcomes are expected to revolutionise RNA manufacturing, develop cutting-edge commercialisable IP, scholarly know-how, and galvanise the Australian biomanufacturing sector towards sovereign capability, biosecurity and commercialisation of new animal, human and plant RNA products.

发展核糖核酸制造和技术创新。该项目旨在通过优化自扩增(SAM)RNA生产以实现低杂质、创建可靠的纯化技术并填补RNA分析中的关键空白，来开发尖端制造和分析技术。该项目预计将生产出更便宜、更高质量的RNA产品，并开发RNA分析的新方法。预计这些成果将彻底改变RNA制造，开发尖端的可商业化知识产权和学术知识，并激励澳大利亚生物制造行业朝着自主能力、生物安全和新的动植物RNA产品的商业化方向发展。