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Mechanotransduction from lysosomes drives sterile inflammation

Mechanotransduction from lysosomes drives sterile inflammation
溶酶体的力传导驱动无菌炎症
批准号:
479441
负责人:
Freeman Spencer A
金额:
$65.76万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01

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中文摘要
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英文摘要
Cells sense and respond to physical forces including stretch, pressure and vibration by converting mechanical signals into electrical signals. Mechanosensing is mostly appreciated to occur at the cell surface, however, subcellular membrane-bound compartme
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Canada Research Chairs - Tier 2
  • 批准号:
    441842
  • 项目类别:
  • 资助金额:
    $43.71万
  • 财政年份:
    2020
  • 负责人:
    Freeman Spencer A
  • 依托单位:
Solute transport in the innate immune response
  • 批准号:
    409332
  • 项目类别:
    Operating Grants
  • 资助金额:
    $55.17万
  • 财政年份:
    2019
  • 负责人:
    Freeman Spencer A
  • 依托单位:
Signaling in macrophages: the role of phosphatase exclusion
  • 批准号:
    335389
  • 项目类别:
    Fellowship Programs
  • 资助金额:
    $10.2万
  • 财政年份:
    2015
  • 负责人:
    Freeman Spencer A
  • 依托单位:
The Role of a Rap1GTP/cofilin actin severing pathway in lymphoma progression
  • 批准号:
    206118
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $7.65万
  • 财政年份:
    2009
  • 负责人:
    Freeman Spencer A
  • 依托单位:
海外基金