A new handle on a known target: structure-based discovery of FPP synthase inhibitors targeting a cryptic pocket
A new handle on a known target: structure-based discovery of FPP synthase inhibitors targeting a cryptic pocket
已知目标的新处理：基于结构的 FPP 合酶抑制剂的发现，靶向神秘的口袋
批准号：
488214
负责人：
Park Jaeok
金额：
$4.55万
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2023
资助国家：
加拿大
项目状态：
已结题
起止时间：
2023-02-01 至 2024-02-01
中文摘要
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英文摘要
Our goal isto find drug candidate molecules that can block an enzyme called farnesyl pyrophosphate synthase. Blocking this enzyme can reduce the cellular activitiesthat cause cancer, making it a promising strategy for treating cancer. We will use an appro
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