Market Assessment Study of Leech-mimic 3D Printed Origami Sensor to Monitor Electrophysiological Signals

西蒙弗雷泽大学技术许可办公室通过NSERC创意创新资助计划支持了Adventus的一项市场评估研究，该研究由SFU机电系统工程学院教授Woo Soo Kim博士开发的一项名为“水蚤模拟3D打印折纸（LMO）传感器”的技术，该传感器由非辅助尖端与辅助体组成，用于监测电生理信号。血压监测在医学诊断中起着至关重要的作用，因为高血压与多种慢性疾病密切相关。随着心血管疾病的日益流行和人口老龄化的加剧，人们对个人医疗保健系统的需求不断增加，这些系统可以在患者的日常生活中收集血压。因此，无需临床设置的准确和/或频繁的血压监测（例如用于远程或一般医疗监测的移动或可穿戴设备）预计将推动全球ECG传感器市场。事实上，ECG和PPG（光电体积脉搏图）技术都变得容易获得，低成本，方便便携式设备。脉冲到达时间（PAT）参数，表示脉冲波形从心脏到远端所花费的时间，通常与成对的ECG-PPG传感系统一起连续监测血压。用PAT监测血压需要可靠的心电信号和远端PPG信号。因此，干燥的ECG电极在皮肤上的稳定定位对于获得有效的ECG信号至关重要。SFU的研究人员开发了一种模仿水蛭的3D打印折纸（LMO）传感器，该传感器由非辅助尖端和辅助体组成，用于监测电生理信号。这种模仿水蛭的结构（LMO）提供稳定的接触，并对人体皮肤施加可靠但轻微的吸力，这样当患者运动时，LMO仍然附着在人体皮肤上。与目前用于ECG和BP监测的湿凝胶型电极相比，这种用于心血管监测系统的干电极使监测时间更快，更舒适。

The Simon Fraser University Technology Licensing Office has Adventus work on a market assessment study supported through the NSERC Idea to Innovation grant program, for a technology entitled "Leech-mimic 3D printed origami (LMO) sensor composed of the non-auxetic tip with auxetic bodies to monitor electrophysiological signals" developed by Dr. Woo Soo Kim, Professor in the School of Mechatronic Systems Engineering at SFU. Monitoring of blood pressure (BP) plays a crucial role in medical diagnosis because high BP is deeply related to several chronic diseases. The increasing prevalence of cardiovascular diseases and the growing aging population are leading to rising demand for personal healthcare systems that collect the BP of patients during their daily life. Therefore, accurate and/or frequent BP monitoring without clinical settings (such as mobile or wearable devices for remote or general healthcare monitoring) is anticipated to drive the global ECG sensor market. In fact, both ECG and PPG (photoplethysmography) technologies are becoming easily available, low-cost, and convenient with portable devices. The pulse arrival time (PAT) parameter, indicating the time taken from the pulse waveforms to traverse from the heart to a distal site, is often used with the paired ECG-PPG sensing system monitoring the BP continuously. The BP monitoring with PAT requires reliable ECG signals near the heart and PPG signals on the distal site. Thus, stable positioning of dry ECG electrodes on the skin is essential to obtain effective ECG signals. SFU researchers have developed a leech-mimic 3D printed origami (LMO) sensor composed of the non-auxetic tip with auxetic bodies to monitor electrophysiological signals. The leech-mimic structure (LMO) provides stable contacts and applies reliable but slight suction to the human skin so that the LMO is still attached to the human skin when the patient is in motion. This dry electrode for cardiovascular monitoring systems makes monitoring time faster and much more comfortable compared to the current wet gel-type electrodes used in monitoring ECG and BP.