Geno-hunting: creating super parents for cannabis-R1

的大麻具有很长的人类使用历史，用于各种应用，包括纤维、食品、药物以及其精神活性特性。尽管其经济，医学和社会重要性，但由于长期的禁令，缺乏严格的研究。不可否认，大麻产业几乎所有方面都缺乏基于经验的最佳做法和优化方案，包括育种和遗传学、种植、加工和收获后。来自近亲繁殖过程的稳定品种为大麻种植者提供了一个独特的机会，不仅可以生产统一的产品，还可以探索大麻遗传学的新组合，以开发抗病性，新的风味和香气，改变大麻素水平，并提高总产量。在这里，我们的目标是1）描述大麻关键性状的遗传基础，为“等位基因挖掘”和基因组学辅助育种打开大门，2）通过在育种计划中采用新开发的基因组学工具，快速将研究转化为实实在在的利益，以开发大麻的近交系和纯种子。这将有助于确保加拿大保持在大麻研究的最前沿，并朝着从克隆繁殖和种植战略过渡到种子系统的长期目标迈进。

Cannabis sativa L. has a long history of human use for a variety of applications including fibre, food, medicine, and for its psychoactive properties. Despite its economic, medicinal, and societal importance, there is a lack of rigorous research due to the long history of prohibition. Scarcity of empirically based best practices and optimized protocols for almost all aspects of the cannabis industry ranging from breeding and genetics, cultivation, processing, and postharvest is undeniable. Stabilized cultivars derived from the inbreeding process represent a unique opportunity for cannabis growers to not only produce uniform products but also explore new combinations of cannabis genetics to develop disease resistance, new flavours and aromas, alter cannabinoid levels, and boost total yields. Here, we aim to 1) characterize genetic basis of key traits in cannabis to open the door for "allele mining" and genomics-assisted breeding, and 2) rapidly translate research into tangible benefits through the adoption of newly developed genomics tools in breeding programs for development of inbred lines and pure seeds in cannabis. This will contribute to ensuring Canada remains at the forefront of cannabis research and move toward a long-term goal of transitioning from clonal propagation and cultivation strategies to a seed-based system.