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Exploiting translational reprogramming in neoplasia to devise unique strategies to eliminate cancer and cancer-promoting senescent cells

Exploiting translational reprogramming in neoplasia to devise unique strategies to eliminate cancer and cancer-promoting senescent cells
利用肿瘤中的翻译重编程设计独特的策略来消除癌症和促进癌症的衰老细胞
批准号:
494900
负责人:
Mallette Frdrick A
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-09-01 至 2024-09-01

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中文摘要
翻译
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英文摘要
Radiotherapy and chemotherapeutic agents target proliferating (as well as non-proliferating) cells in a non-specific manner, triggering permanent cell cycle arrest in both normal and cancer cells. While cancer therapy exerts beneficial effects by preventi
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会议论文
Identifying novel therapeutic vulnerabilities in pediatric acute megakaryoblastic leukemia
Canada Research Chairs - Tier 2
  • 批准号:
    441821
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2020
  • 负责人:
    Mallette Frdrick A
  • 依托单位:
Cholesterol metabolism and regulation of the senescence-associated secretory phenotype in retinopathy
Cholesterol metabolism and regulation of the senescence-associated secretory phenotype in retinopathy
海外基金