Cholesterol metabolism and regulation of the senescence-associated secretory phenotype in retinopathy
视网膜病变中胆固醇代谢和衰老相关分泌表型的调节
基本信息
- 批准号:418822
- 负责人:
- 金额:$ 63.25万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2020
- 资助国家:加拿大
- 起止时间:2020-03-01 至 2025-03-01
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Deficient blood supply to the central nervous system (CNS) leads to several debilitating diseases. Examples of such diseases include stroke which is a leading cause of brain injury affecting 800,000 individuals per year in the United States alone and caus
中枢神经系统(CNS)的血液供应不足会导致几种使人衰弱的疾病。这些疾病的例子包括中风,这是脑损伤的主要原因,每年仅在美国就有80万人受到影响
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Mallette Frdrick A其他文献
Mallette Frdrick A的其他文献
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{{ truncateString('Mallette Frdrick A', 18)}}的其他基金
Identifying novel therapeutic vulnerabilities in pediatric acute megakaryoblastic leukemia
确定儿童急性巨核细胞白血病的新治疗漏洞
- 批准号:
494453 - 财政年份:2023
- 资助金额:
$ 63.25万 - 项目类别:
Operating Grants
Exploiting translational reprogramming in neoplasia to devise unique strategies to eliminate cancer and cancer-promoting senescent cells
利用肿瘤中的翻译重编程设计独特的策略来消除癌症和促进癌症的衰老细胞
- 批准号:
494900 - 财政年份:2023
- 资助金额:
$ 63.25万 - 项目类别:
Operating Grants
Cholesterol metabolism and regulation of the senescence-associated secretory phenotype in retinopathy
视网膜病变中胆固醇代谢和衰老相关分泌表型的调节
- 批准号:
414851 - 财政年份:2019
- 资助金额:
$ 63.25万 - 项目类别:
Operating Grants
Establishing a new class of senolytics to treat age-related pathologies and extending lifespan
建立一类新的 senolytics 来治疗与年龄相关的病症并延长寿命
- 批准号:
398880 - 财政年份:2018
- 资助金额:
$ 63.25万 - 项目类别:
Operating Grants
Identification of therapeutic targets for pediatric acute megakaryoblastic leukemia
儿童急性巨核细胞白血病治疗靶点的确定
- 批准号:
370619 - 财政年份:2017
- 资助金额:
$ 63.25万 - 项目类别:
Operating Grants
The role of the JMJD2 family of lysine demethylases in senescence and cancer
赖氨酸脱甲基酶 JMJD2 家族在衰老和癌症中的作用
- 批准号:
290927 - 财政年份:2013
- 资助金额:
$ 63.25万 - 项目类别:
Operating Grants
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ICF:中性粒细胞和细胞衰老:促进与年龄相关疾病的恶性循环。
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Fellowship
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阐明谷氨酰胺分解在神经胶质细胞衰老中的作用及其对年龄相关神经变性的贡献
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23K10827 - 财政年份:2023
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$ 63.25万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Mechanisms of Cellular Senescence Driving Intervertebral Disc Aging through Local Cell Autonomous and Systemic Non-Cell Autonomous Processes
细胞衰老通过局部细胞自主和全身非细胞自主过程驱动椎间盘老化的机制
- 批准号:
10635092 - 财政年份:2023
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Role of DNA damage and cellular senescence in osteoarthritis pathophysiology
DNA 损伤和细胞衰老在骨关节炎病理生理学中的作用
- 批准号:
10801026 - 财政年份:2023
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Elucidation of the mechanism underlying cellular senescence and aging induced by the continuous DNA damage
阐明持续DNA损伤引起的细胞衰老和老化的机制
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22KJ0646 - 财政年份:2023
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Grant-in-Aid for JSPS Fellows
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自闭症谱系障碍的病理生理学重点关注细胞衰老和寻找新的治疗方法
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23K14811 - 财政年份:2023
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The role of cellular senescence of vascular endothelial cells in idiopathic pulmonary fibrosis and complicated pulmonary hypertension.
血管内皮细胞衰老在特发性肺纤维化和复杂性肺动脉高压中的作用。
- 批准号:
23K15189 - 财政年份:2023
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Roles of aging and cellular senescence in the development of intracranial aneurysm rupture
衰老和细胞衰老在颅内动脉瘤破裂发展中的作用
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10680060 - 财政年份:2023
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Regulation of cellular senescence and metabolic health by dietary protein
膳食蛋白质调节细胞衰老和代谢健康
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