将具有催化活性的结构单元合理地引入到苯乙烯类单体的结构中，分别通过可控自由基聚合反应、螺旋选择性聚合反应或它们二者的结合，获得核壳型多臂星状手性聚合物刷、光学活性螺旋链聚合物和核壳型多臂星状光学活性螺旋链聚合物刷。研究含极性功能团单体的螺旋选择性离子聚合，发展对聚合物螺旋结构的直观表征方法，建立调控聚合物拓扑结构、立体结构的简便、有效手段。用所得到的光学活性聚合物为催化剂，探索其在羟醛缩合、烷基化、环氧化、还原、氢化、硅氢加成等几类典型不对称有机反应中的应用，系统研究聚合物化学结构、拓扑结构、立体结构与催化效率和对映体选择性之间的关系。结合理论分析和计算机模拟，深入理解螺旋选择性聚合反应和不对称合成过程中的手性传递与放大的机制，为获得化学结构稳定、立体结构可控、催化效率高、对映体选择性专一、易于循环使用的高性能不对称合成催化剂提供理论依据和新的途径。

In this project, styrene derivatives bearing active sites for asymmetric synthesis are designed and prepared. Core-shell multi-arm star chiral polymer brushes, optically active helical polymers, and core-shell multi-arm star optically active helical polymer brushes are obtained via controlled radical polymerization, helix-sense-selective polymerization or/and their combination, respectively.Helix-sense-selective ionic polymerization of styrenic monomers with polar functional groups is systematically investigated. An efficient and facile strategy to tune the stereostructures of the resultant polymers is developed. These optically active polymers are employed to catalyse chemoselectively and stereospecifically some typical organic reactions, such aldol reaction, allylic amination, epoxidation, reduction, hydrogenation, and hydrosilylation, which frames their application in asymmetric catalysis. The study is also dedicated to the direct observations of helical structures of polymers and the in-depth understanding of chirality transfer during either helix-sense-selective polymerization or chiral synthesis. The success of this project will prompte the exploration of new systems for polymer-based catalysts and of new functions of helical polymers. It will also refuel the current chiral synthesis, which is at the heart of contemporary organic chemistry.