带有功能性基团的磁性四氧化三铁/聚合物核壳型杂化微球的合成及其应用性能的研究

磁性Fe3O4/聚合物核壳型杂化微球由于具有独特的性质，在可控药物释放、纳米反应器、核磁共振成像等领域有着广泛的应用，有关其合成与应用性能的研究是高分子材料研究领域的前沿性课题。本项目拟结合可控的溶剂热解法、蒸馏沉淀聚合法、表面接枝的活性ATRP聚合法等，合成得到以磁性Fe3O4为核、聚合物壳层为带有不同功能基团的Fe3O4/聚合物杂化微球，研究多层杂化微球的合成过程中的聚合反应机理。进而，拟开展该类功能性杂化微球作为金属纳米胶体的稳定剂及其催化性能、可控药物释放载体以及核磁共振成像等领域的应用性能。

The synthesis and application of magnetic/polymer hybrid core-shell microspheres have been a frontier research field in the polymer chemistry and material due to their unique properties for many areas, such as controlled durg release reservior, nano-meter reactor, magnetic resonance imaging, etc. In this project, the combination of the controlled solvothermal hydrolysis, distillation precipitation polymerization, the surface-initiated atom transferring radical polymerization (ATRP), will be used for the preparation of magnetite/polymer hybrid core-shell microspheres with a strong magnetic core and polymer shell-layer having various functional groups. The formation mechanism for the construction of Fe3O4/polymer core-shell microspheres will be performed. Further, the applications of these core-shell microspheres as the support for the gold nanometallic colloids and their catalytic property, the controlled drug release reservior, and the magnetic resonance image reagent, will be investigated.