低温/电场复合作用下折柔性人工晶状体的流变液抛光机理及调控方法研究

折柔性非球面人工晶状体具有手术切口小、折射率高、改善视觉质量等优点，是目前白内障晶状体植入手术中使用的主流人工晶状体，而我国软性人工晶状体的研发尚处于起步阶段。人工晶状体的光学性能主要依靠对其光学面进行抛光获得，而人工晶状体在常温条件下刚性弱、硬度低，现有的抛光方法极容易造成表面损伤和过抛等现象，严重影响它的光学性能和生产效率。本项目针对这一难题，提出一种利用电流变效应生成的可控柔性抛光头在低温条件下对人工晶状体进行抛光的新方法。围绕着低温/电场复合作用下折柔性人工晶状体流变液抛光的学术思想和技术实现模式，开展电流变效应作用下的固液两相粘性磨料流特性与磨粒动力学行为、粘性磨料流与不同温度软性晶状体的界面作用机理、电流变抛光人工晶状体的表面粗糙度和面型精度调控机制及其生物相容性评价等前沿性研究，开发人工晶状体电流变抛光装置，为折柔性人工晶状体的高效精密加工提供了新原理和新方法。

Aspheric foldable intraocular lens (IOL), which has the advantage of high refractive index, small surgical incision and high visual quality, is currently the mainstream lens used in the intraocular lens implant surgery. The research and development of China's soft IOL is still in its infancy. The optical performance of the IOL mainly depends on the polishing of the optical surface. However, the IOL is weak in rigidity and low in hardness at normal temperature, and the existing polishing methods exist the phenomena of surface damage and polishing marks caused by the poor polishing conditions, which seriously affect the optical performance and production efficiency of IOL. In order to solve this problem, a new method of polishing the IOL by a controllable flexible polishing head generated by the electrorheological effect at low temperature is proposed. Around the new method and academic thought, the research contents of the project include the rheological properties of two-phase viscous abrasive flow and the kinetic behavior of abrasive particles under electrorheological effect, the interface mechanism between the viscous abrasive flow and soft IOL surface in different temperatures, and the regulation mechanism of surface roughness and form accuracy for the electrorheological polishing process. In this project, the IOL electrorheological polishing device is developed. The project provides new principles and new methods for manufacturing the flexible intraocular lens with the high precision and efficiency.