海洋天然高分子等生物质资源的开发利用意义重大。天然高分子具有较好的稳定性和可加工性能，但作为药物载体其孔道/孔洞大小和分布不均一；与之相反，金属-有机骨架(MOFs)化合物具有特定的孔道/孔洞结构，并具有结构丰富、性能可调等特点，但一般MOFs的稳定性和可加工性不好。本项目将充分发挥MOFs和天然高分子各自的优势，充分利用广西丰富的甲壳素、海藻等海洋天然高分子资源，采用可控有序的原位复合方法，构建优势互补的MOFs-天然高分子新型复合材料。研究金属离子与天然高分子的相互作用及其对可控制备的影响，以及新型复合材料对药物分子的识别、吸附与缓释等性能，探讨其在亚热带水果保鲜方面的应用，建模阐述新型复合材料的结构与药物缓释及其与水果保鲜效果的关系。本项目的实施将为海洋天然高分子等资源的开发利用、地方产业与经济发展等，提供科学依据和指导，研究成果有重要的科学意义和潜在的应用价值。

It is of great significance to develop and utilize marine natural polymer and other biomass resources. Natural polymers have good stability and processability, however, as a drug carrier, the size and distribution of the pore are not uniform. On the contrary, the metal-organic frameworks (MOFs) have specific pore structure, rich structure, adjustable performance and so on. But in general, the stability and machinability of MOFs are not good. The project is to prepare the novel composites of MOFs-natural polymer with complementary advantages by in-situ recombination method with controllable order, which will make full use of the rich marine natural polymer resources such as chitin, seaweed and so on in Guangxi. The influence of the interaction of metal ions with natural polymer on the controllable preparation of the composites is studied. The recognition, adsorption and sustained-release properties of target drug molecules by the composites and their application in preservation of subtropical fruits are also investigated. In addition the relationship between the drug sustained-release properties and the fruit preservation effect is established. The results of this project will have important scientific significance and potential application value for the utilization of marine natural polymer resources and local industry and economic development, etc.