生物对持续变化环境的适应是进化生物学领域的研究热点和难题。以世界潮间带物种多样性最丰富的印度-西太平洋(IWP)地区的木本植物红树为研究对象，在已测定和获得了的3种代表红树植物全基因组序列和已有的群体基因组学理论研究平台的良好基础上，采用基于第二代测序技术的群体基因组重测序方法，结合数学建模和计算机模拟，在包含3种经典地理模式(异域、邻域和同域式物种形成)的特殊研究系统中，从全基因组的角度解析生物对持续变化的环境适应的基因组机制，揭示IWP地区潮间带物种多样性极高的历史和进化原因；在此基础上和以该地区红树植物为观测系统，提出、建立和检验生物适应变化的环境的物种形成新理论模型。这一研究将对从全基因组层面全面认识生物在自然界持续变化的环境中生存、适应和演化模式与机制提供有价值的重要理论方法与实证。

Adaptation to continuously changing environments is one of the hottest topics and also the most difficult issues in evolutionary biology. In this study, we will use mangroves as a study system from the Indo-West Pacific (IWP) region, where biodiversity is the richest in global intertidal zones. Based on the available whole genome sequences of three typic mangrove species and population genetics data, we shall use next-generation highthroughout re-sequencing and population genomics analysis approaches, combining with math model and computer simulation in special research systems including three classical geographical patterns (allopatric, sympatric, parapatric speciation), to study the genomic mechanisms of adaption of these important intertidal species to continuously changing environments, and reveal historical and evolutionary causes why there is an extremely high biodiversity of species in the intertidal zones of the IWP region. With the observation system of mangrove population genetic patterns in genomic level in this region, we will raise, construct and test new theoretical models of speciation mechanisms of adaptation to continuously changing environments. This research will provide valuable and significant theoretical approaches and examples in understanding the patterns and mechanisms of organisms to survive, adapt and evolve in continuously changing environments.