本项目通过动物及人体数据采集，研究建立具有腰椎、椎间盘、肌肉、神经所构成的系统解剖与生理特征的生物力学模型，把L4-5椎间盘及邻近的肌肉和神经组织为一个生物系统整体，用有限元法对该整体进行分割离散，每个有限元为一个LRC基本单元，利用肌电图检测神经的电活动，利用应变片检测x，利用力传感器检测F，由此建立腰椎间盘的基于神经反馈控制的生物力学模型。并运用所建立的模型，研究杠杆定位手法与平面力手法（大鱼际揉法）所产生的仿真效果，分析这两种手法生物力学的差异性；揭示杠杆定位手法对腰椎间盘影响的机制，为正确分析手法的临床合理性提供依据，为手法标准化、操作规范化、流程科学化提供基础。同时，通过本项目明确杠杆定位手法对腰椎间盘作用的关健点，为今后杠杆定位手法在腰椎间盘突出症的临床应用提供科学依据。

The aim of the study is to establish a biomechanical model with physiological and anatomical characteristics of lumbar intervertebral disc, muscle,and nerve system by collecting data of animal and human.Take L4-5 intervertebral disc and adjacent muscle and nerve tissue as a whole of biological system.and discrete split on the overall by means of finite element.so each finite element will be the basic unit of an LRC.Detect the electrical activity of nerve by EMG,detect X by strain gauge,detect Y by force sensors,and then a biomechanical model based on neural feedback control will be established.Meanwhile,this study is to analysis simulation results and biomechanical differences of manipulation of lever location and plane forces through this model,which will reveal the mechanisms of effect of manipulation of lever location on the lumbar intervertebral disc and provide the basis for analysis of rationality of manipulation which will promote standardization of manipulation.meanwhile,this study make the key points of effect of manipulation of lever location on the lumbar intervertebral disc clear,which will provide a scientific basis for future treatment of lumbar disc herniation.