迄今为止，我国已发现的苦苣苔科植物共有58个属 (其中27个属为我国特有属)，600余种，是喀斯特地区的特征类群之一。贵州是我国的喀斯特省，喀斯特地貌分布占全省面积的61.92%，苦苣苔科植物研究极少，由于喀斯特地区苦苣苔科植物多分布狭窄，资源极易破坏，许多新的物种和潜藏的药用知识亟待发现并制定保护策略。申请者前期对贵州部分喀斯特地区的苦苣苔科植物做了初步调查，对贵州两种野生苦苣苔植物提取部位的药理功效和化学成分做了初步研究，首次发现其提取物和化学成分在体外表现有明显的抗病毒活性，提示苦苣苔科植物在开发抗病毒药物方面有很大的开发潜力。本申请拟采用民族植物学方法对贵州喀斯特地区苦苣苔科传统药用知识进行系统的调查编目；用现代的植物化学和药理学手段分析其特征成分并评价和验证其药用功效，以期发现具有喀斯特地区特色的苦苣苔科药用植物新资源，验证药材的道地性，并为其质量控制和可持续利用提供科学依据。

So far, there is about 58 genera and more than 600 species of Gesneriaceae were found in China, of these, 27 genera are endemic to China. Gesneriaceae is one of the characteristic groups distributed in karst region. Guizhou is the karst province of our country, the distribution of Karst geomorphology accounts for 61.92% of the province's area, and very little research has been done on the Gesneriaceae plant in Guizhou. Due to the narrow distribution of Cesneriaceae in karst area, the resources are extremely vulnerable to destruction, a lot of new species and hidden medicinal knowledge need to be discovered and protected. The applicant made a preliminary investigation on the plants of Cesneriaceae in some karst areas of Guizhou Province, and a preliminary study on the pharmacological effects and chemical constituents of the extract parts of wild Lysionotus pauciflorus and Briggsia mihieri in Guizhou was carried out , it was found that the extracts and compounds of Lysionotus pauciflorus and Briggsia mihieri showed obvious anti-virus activity in vitro for the first time, it is suggested that there is great development potential in medicinal value of Cesneriaceae plants. This application intends to use ethnobotanical methods to systematically investigate and catalogue the traditional medicinal knowledge of the family Cesneriaceae in karst areas of Guizhou Province, analysis of its characteristic components by phytochemical method, and evaluation and verification of its medicinal efficacy by pharmacological means, to provide the scientific basis for the rational development and utilization of the medicinal resources of Cesneriaceae plants.