全氟化合物(PFCs)是一类新型的环境污染物，对生态环境和人体健康构成潜在危害。过去大量的研究都是将PFCs看成单一化合物进行探讨，没有区别其异构体的组成和行为差异。因此，对于PFCs异构体的环境行为差异的认识还非常有限。本项目拟通过野外调查和实验室模拟实验相结合，探索PFCs碳链异构化和水化学条件对其吸附行为的影响规律；系统研究支链/直链异构体PFCs在水体多界面间分配行为的差异；通过实验室模拟培养不同的水生生物，考察PFCs碳链异构化与其生物富集、代谢、降解等行为间的相互关系。并研究在食物链传递过程中PFCs分异特征及与异构体结构之间的相互关系。在此基础上，对我国典型水体环境中PFCs的来源进行解析。本研究将为准确解析环境中PFCs的污染历史和来源提供理论基础，为科学进行PFCs的环境风险评估和环境管理提供科学依据。

Perfluorinated compounds are a group of emerging environmental pollutants, which may pose adverse effects to wildlife and human. Earlier studies about PFCs in the environment focused primarily on the detection of all PFCs as single compounds without further differentiation of their isomers. Little is known about the differences in environmental behaviors of PFC isomers. The objectives of this project are to study the impacts of the isomerization of PFCs and water chemistry on their sorption on sediment and distribution between multiple phases in water; to investigate the differences in bioaccumulation, elimination and degradation of PFC isomers in biota and also to study the fractionation of PFC isomers along food chain. Based on the research results, quantitative assessment of manufacturing sources would be made to the studied watersheds. The research results of this project will lay theoretical basis for accurate assessment of pollution history and manufacturing sources. They also provide scientific evidences for management and risk assessment of PFCs in the environment.