合成气制低碳醇催化剂的关键是提高C2+醇的选择性。铜钴双金属催化剂中，铜和钴协同催化生成低碳醇，所以要求铜钴形成合金或密切接触。本项目提出了Cu-Co催化剂设计的新构想：将纳米LaCo1-xCuxO3（钙钛矿型复合氧化物-PTO）晶粒负载于ZrO2、SiO2等载体上，然后还原可得负载型Cu-Co纳米合金或纳米核壳结构等。因为：LaCo1-xCuxO3中，铜和钴离子处于原子水平的均匀混合，且二者被限域于纳米晶粒内。助剂也可以作为PTO的取代离子加入，以利于助剂与活性组分相互作用。申请人按本构想制得的催化剂具有很高的C2+醇选择性及较好的活性，很有应用前景。本项目将在此基础上重点研究催化剂的稳定性，研究催化剂结构和性能随反应时间的演化、构效关系、助剂和载体的作用等，为中试试验提供基础和进一步优化催化剂。学术价值：本方案可拓展于其它纳米双金属的制备，因为大部分金属离子可以是PTO的晶格离子。

The critical challenge for the catalyst for higher alcohols synthesis is improving the selectivity to higher alcohols in which one alcohol molecule has two or more then two carbon atoms. Over bimetallic Cu-Co nano catalyst, higher alcohols are generated by copper and cobalt synergistic catalyzing, so it is required that copper and cobalt are in the alloy state or nano particles with copper and cobalt being closely linked. We proposed a new scheme for designing Cu-Co bimetallic catalyst: to load a perovskite-type oxide (PTO) of LaCo1-xCuxO3 on a support such as ZrO2 or SiO2, and then to reduce it, thus supported nano particles of Cu-Co alloy or nano particles with core-shell structure can be made. This is owing to that in LaCo1-xCuxO3 copper and cobalt ions are uniformly mixed at atomic level and that copper and cobalt ions are confined in a nano particle. Additives of the catalyst can also be added as substitution ions of the crystalline lattice in the PTO, which favors the interaction between the additives with the active components. Based on this scheme, we have prepared bimetallic Cu-Co nano catalyst, and the catalyst showed much high selectivity to higher alcohols and very good activity, suggesting that it is a much promising catalyst for industrial application. In this project, we will investigate the stability of the catalyst, to study the variation of the structure and the catalytic performance of the catalyst with reaction time, to study the relationship of the structure and the catalytic performance of the catalyst, and to study the effects of additives and support, in order to obtain basic data as preparatory work for undertaking scale-up test, and to further improving the catalyst. The scheme proposed in this proposal can be applied to many other bimetallic/multi-metallic nano particles, for that most of the metal ions can be acted as the crystalline lattice ions of a PTO, so the study of this project is of great significance in the aspect of academic viewpoint.