本项目拟通过调节并优化有机硒化合物中的取代基结构，发展一种可以同时进行共轭和非共轭乙烯基单体活性自由基聚合的调控试剂；建立有机硒化合物调控的活性自由基聚合体系；利用通用型有机硒化合物调控剂开展聚合物合成设计，制备由共轭和非共轭乙烯基单体组成的嵌段共聚物。通过本项目的研究，可以发展和丰富活性自由基聚合研究，并通过扩大聚合方法的单体适用面，提升活性自由基聚合方法的操作便利性，简化复杂聚合物合成步骤，为聚合物合成方法提供新途径。相对于已有活性自由基聚合体系，该项目开展的研究具有调控剂制备过程简便、聚合条件温和便利、可适用单体面广等优点。

This proposal is aimed to developing universal mediator based on the organo-selenium compounds for the living polymerization of both the conjugated and unconjugated vinyl monomers.It was found from the preliminary work that the substitution groups in organo-selenium mediator showed as a crucial factor for their perfomance in living free radical polymerization. By changing the substitution groups in organo-selenium compounds from N,N-diethyl to ethoxy, the compounds showed corresponding controllability migration from conjugated monomers to unconjugated monomers.Such interesting results inspired us to carry out detail work for the investigation of the effect of substitution groups structure on the organo-selenium compounds properties using as the mediator for living free radical polymerization. The basic rules for the structure selection in organo-seleium for the living free radical polymerization of specific monomer will be figured out. Based on the rules, structure of the organo-selenium compounds will be optimized for the developing of universal mediator. By using these universal mediator, block copolymers consisted with conjugated and unconjugated monomers was proposed to synthesize under the controlled manner. The rules and conditions for the preparation of such kind block copolymer will be optimized. Compared with the existing living free radical polymerization techniques, the current proposal showed advaces in: 1) well stability of the mediator compared with the organo-tellerium compounds; 2) mild polymerization conditions and easy for handle procedures compared with the organo-sulfur mediators; 3) advaces in the design and synthesis of selenium-containing polymers, which was reported as the interesting enzyme-responsive polymers showed potentially application as bio-related materials.