作为多细胞生命体，植物能对局部非生物性胁迫产生系统性反应，以更好的抵抗或适应环境压力，但其内在机理和关键环节尚有许多重要问题亟待解答。通过对现有研究的分析来看，胞外ATP及其受体的诸多特性使胞外ATP很可能在植物这种系统性反应的信号引发、传递和感知等环节中均扮演着重要的角色，同时也使胞外ATP具有以“自延伸”方式在细胞间进行传递并调节这种系统性反应的潜力，且其较之其它相关信号分子处于上游的位置并更加特异和敏感。据此，本项目提出一个尚未探索但很可能存在的重要机制：在局部非生物性胁迫引起的植物系统性反应中，胞外ATP通过其受体DORN1的介导，以“自延伸”方式形成了一种从胁迫位点向系统位点传递的“胞外ATP波”，并由此调控了植物的这种系统性反应。相信对该机制的探索将使植物这种系统性反应的内在机制得到更加充分和深入的认知，而这也将极大丰富对植物胞外ATP功能的理解并为其它相关研究提供重要的借鉴。

As multicellular organisms, plants have systemic responses to local abiotic stresses, which improve the resistance or acclimation of plants to environmental stresses. However, there are many important questions about the internal mechanisms and key events for such systemic responses. Based on the analyzation of the current researches and many characteristics of plant extracellular ATP and its receptor DORN1, plant extracellular ATP could play important rols in the initiation, transmission, and perception of the signals for the systemic responses of plants to local abiotic stresses. And, the features of extracellular ATP and DORN1 also make extracellular ATP have a potential to form autopropagating signals via cell-to-cell communication and thus mediate such systemic responses of plants. Moreover, due to these characteristics, in the plant systemic responses to local abiotic stresses, extracellular ATP could act as an upstream signaling and be more specific and sensitive than other related signaling molecules. Based on the reasons above, we propose an unknown but imporant mechanism as described below. In the systemic responses of plants to local abiotic stresses, there may exist an “extracellular ATP wave”, which is formed by extracellular ATP autopropagation dependent on the mediation via receptor DORN1. Such “extracellular ATP wave ” can travel from the stressed sites to the systemic sites and be involved in the regulation of the systemic responses of plants to local abiotic stresses. We believe that this research would further develop and expand the current knowledge about the internal mechanism of the plant systemic responses to local abiotic stresses. And, this research would be helpful in developing new understanding about the function of plant extracellular ATP and might provide some valued references for other related researches.