微流控系统的介电泳技术对生物颗粒操控是当前生物，医学，化学，流体，电学等领域的交叉前沿课题之一。大数量密集颗粒群在电场中介电干涉行为与单颗粒完全不同，至今没有很好解决。本课题拟采用理论，数值分析和 PIV 模型实验开展密集介电泳颗粒相互干涉现象研究，研发一种简单实用的密集颗粒群介电力（介电力矩）新算法和颗粒运动实验观测。研究内容：.（1）大数量随机分布密集颗粒群的介电力（介电力矩）创新算法（迭代偶极矩法）研究，包括 二维（三维），直流（交流），均匀（非均匀）电场；.（2）研究在电场介电力和流体力联合作用，大数量密集颗粒群的运动（包括颗粒干涉），颗粒融合（成链，成簇，成团）规律特性研究，包括颗粒大小，数量，颗粒和流体的介电系数，电导率，电场频率，颗粒分布位置等综合因素对颗粒群介电泳特性的影响；.（3）大数量密集介电泳颗粒在电场中相互干涉运动的实验观测。

Bio-particle manipulation of dielectrophoresis in microfluidics is one of frontier research fields of multi-physics interaction associated with biology, chemistry, fluids and electricity. The interaction behavior of dense particle group under combinative action of fluid force and electrical force is one of the most crusal technologies in this field. This research project will study general behavior of electrophoretic particle interaction by theoretic study, numerical analysis and PIV model experiments, develop a simple and parctical algorithm for dielectrophoretic forces of dense particles. This project includs :.(1) innovation algorithm (iterative dipole moment method) for dielectrophoretic forces of a large number of randomly distributed dense particles(2D(3D), direct current(DC), alternating current (AC), uniform(non-uniform) electric field)..(2) General electrokinetic behavior of particle interaction under combinative action of fluid force and electrical force in microfluids, including qualitative and quantitative effects of various design and working parameters ( particle size, distribution of particles, property parameters of particle and buffer solution ) on particle interaction behavior..(3) Experimental study of general behavior of electrophoretic particle interaction subjected to electrical and fluidic forces in microfluids.