本项目针对单组份低维过渡金属二硫属化合物（TMDs）存在的可见光利用率不高、光生载流子易复合、光电转换效率低等问题，结合当前材料研究新热点以及生物医学领域对大分子检测、诊断与预测的迫切需求，拟采用元素掺杂与合金化等成分调控策略，合成出一系列低毒、高质量的低维多元TMDs可见光活性光电材料，基于能带工程提升可见光吸收利用率；基于功能导向的结构设计与先进的纳米加工技术，构筑异质结构复合光电体系，一方面通过耦合一些特殊的效应，进一步提高可见光吸收性能；另一方面利用材料功函数差异形成界面电场，增大光生载流子分离驱动力，抑或通过改善界面传输性能来抑制电子-空穴复合损失，全面提升载流子分离效率，揭示电荷分离、传输及复合机制，研制高性能异质结构光电极，建立生物大分子识别与检测机制。项目研究可加深对光电转换、生物识别与检测等基本科学问题的认识，相关成果将在生物检测、疾病诊断与疗效预测等领域具有应用价值。

Herein, to overcome the disadvantages of low efficiency for visible light utilization, easy combination of photo-induced charges, low photoelectric conversion efficiency of binary low dimensional transition metal dichalcogenide (TMDs) photoactive materials, we propose to synthesize high quality low dimensional TMDs multinary materials with low-toxicity and high visible light absorption via chemical doping and alloying strategies, and construct heterostructures with oxide/sulfide semiconductors and noble metals nanoparticles/carbon nanostructures to proliferate photoelectric conversion efficiency. The project aims at developing high-performances heterostructured photoelectrodes for efficient photoelectrochemical recognition and specific detection of biomacromolecules, based on recent research hotspots on low dimensional materials, as well as imperious demands on biomedical detection, diagnosis and forecast. The TMDs/oxide (or sulfide) heterostructure is designed to increase driving force for photo-induced charges separation and inhibit electron-hole recombination, while combination of noble metals nanoparticles (or carbon nanostructures) in heterostructures will not only facilitate the transport of photo-induced charges at interfaces, but also improve light absorption capacity due to coupling certain effects including localized surface plasmon resonance. The effect of band gap engineering on visible light absorption property will be studied, and the mechanism of photo-induced charge separation and transport will be revealed. High-performance heterostructured photoelectrodes will be fabricated, and several mechanisms for photoelectrochemical recognition and specific detection of biomacromolecules will be established. The study will not only enrich the family of low dimensional TMDs materials, but also gain an insight into photoelectric conversion, biomacromolecule recognition and specific detection. The results may have great potential in biomedical detection, diseases diagnosis, and curative effect forecast etc.