螺烯是苯环以邻位稠合的方式形成的一类非平面螺旋形多环芳香化合物， 由于分子内较大的空间位阻斥力导致π体系产生扭曲构象从而产生手性，这类分子由于其特殊的光学和物理化学性质使得它们在材料化学、分子配体和手性催化以及超分子化学方面显示出巨大的应用前景。因此本项目希望在前期Grubbs 催化剂参与的多取代苯和苯并菲合成的基础上，通过对底物的设计，发展高效的新型C3对称的螺烯衍生物合成方法学。从芳基炔类化合物出发，通过构建[4+2]环化反应生成联苯，再分子内scholl反应的策略来合成不同类型的手性螺烯衍生物。同时我们也将进一步探索在scholl关环反应中涉及到的区域选择性问题以及高光学活性的C3对称的螺烯类化合物的手性拆分和直接合成。此外，我们还将对这类手性螺烯衍生物的光谱性质和光电性能开展研究。

Helicenes are polycyclic aromatic compounds with nonplanar screw-shaped skeletons formed by ortho-fused benzene or other aromatic rings. The chirality of the helix is mainly due to a conformational distortion of the π-system imposed by an intramolecular steric repulsion. Their exceptional chiroptical and physicochemical properties has encouraged their expanding utilizations in many fields, such as materials chemistry, helicene ligands and asymmetric catalysis, supramolecular chemistry. The project wants to develop high effective methodology for the synthesis of novel C3-symmetric chiral helicenes based on our previous research about the synthesis of polysubstituted benzene and triphenylene catalyzed by Grubbs catalyst. Starting from various arylethynylenes, we hope to synthesize various novel chiral helicenes via construction of polyphenyl through [4+2] cyclization reaction, followed by an intramolecular Scholl reaction coupling strategy. At the same time, we will further explore the unexpected regioselectivity in Scholl reactions as well as the chiral resolution and highly enantioselective synthesis of the C3-symmetric chiral helicenes. In addition, we will carry out research on spectroscopic and photoelectric properties of prepared chiral helicenes.