专化品生产是浙江省民营经济的重要板块，多个专化品产量位居全球第一。但是，专化品生产也面临着生产效率低下、产品附加值低、能耗污染严重、安全环保压力大等困难和挑战。本项目将探索如何将高端自动化技术有效融入专化品工业化生产，推动专化品企业产品技术转型、实现节能减排和安全、环保运行，对推动浙江省的传统产业升级、构建绿色经济提供方法与技术保障。本项目将围绕专化品生产中的过程特点和操作难点，从先进控制层、运行优化层、决策调度层、过程集成层、在线监控层等多个方面进行分布式协同调控与智能集成优化理论与方法研究，包括：循环混杂操作下的分布式协同控制、多产品变流程柔性生产过程的智能优化调度、全流程能质交换网络的协同设计与集成优化、面向安全环保指标的异常工况智能诊断和调控。在上述理论方法研究的基础上，形成专化品生产过程高端工业自动化集成技术，并在中间体生产这一典型装置上进行应用示范。

Specialty chemicals industry is an important component of the economy of Zhejiang Province. Many products have become the largest volume ones in the world. However, the plants also face the difficulties and challenges for the low competitiveness and high pressure in safety, pollution, and energy cost. In this project, how the advanced automation techniques can be well applied into the specialty chemicals production is studied. By analyzing the features of the process, the project is planned to develop theory and methods by investigating different layers of the automation, including advanced control, operational optimization, production scheduling, process integration, and online monitoring. The detailed contents include the following issues. To deal with the control of the long flowsheet with a large number of units including both continuous and batch operations, a distributed cooperative control strategy will be developed. To optimize the profit, an integration of the production scheduling and dynamic optimization for process transition will be studied. To reduce the energy and waste, the synchronized design of the heat and mass exchanger networks will be synthesized. To meet the requirement of safety and environment, online monitoring and diagnosis of the safety and environmental indexes will be developed. Finally, the proposed methods will be demonstrated on a chemical intermediate plant.