微量元素失衡是外源污染物对植物产生毒性效应的重要诱因，深入考察手性除草剂对植物体内微量元素的选择性扰动特征并揭示其与对映体毒性效应间的关联，对于科学评估手性农药环境生态风险十分必要。因此，本研究拟选择拟南芥和大豆作为指示生物，聚焦对植物生长最为重要的微量元素铁，考察典型手性除草剂异丙甲草胺、2,4-滴丙酸甲酯及咪唑乙烟酸对植物体内微量元素吸收、输运、聚集等扰动特征。以脂肪酸代谢为切入点，探讨代表性含铁大分子P450酶在手性除草剂对植物体内铁元素选择性扰动中起到的介导作用，结合手性除草剂与P450酶、乙酰辅酶A羧化酶和脂肪酸的相互作用研究，揭示P450酶介导的手性除草剂对脂肪酸代谢的调控及手性除草剂生态毒性效应对映体选择性的机制。这些问题的顺利解决将有助于全面认识手性农药的环境生态风险，为手性农药的环境安全性评价提供科学基础。

The micronutrients disturbance is a key factor to cause toxic effects for plants during their exposure to pesticides. Thus, it is of great importance to investigate the selective perturbation effect of chiral herbicides on trace elements in plants, as well as the correlation between micronutrients disturbance with enantioselective toxic effects. Herein, this study is aimed to investigate the effects of the typical chiral herbicide on micronutrients disturbance for plants. Arabidopsis thaliana and soybean are set as the biological indicator, the important trace element Fe for plant growth is the major element which we will focus on, and metolachlor, 2,4-demethylpropionate and imazethapyr are chosen as typical chiral herbicide. Further, fatty acid metabolism is focused in order to account for the mediate role of P450 enzymes in the selective disturbance of trace element Fe in plant which was brought by chiral herbicides. The interaction between chiral herbicides with P450 enzymes, acetyl-coenzyme A carboxylase and fatty acids will be explored to reveal the behavior perturbation of trace element Fe in plants by chiral herbicides and mediate role of cytochromes P450. It will present a promising cognition for the environmental ecological risks of chiral pesticides and provide a scientific reference for the environmental safety evaluation of chiral pesticides.