包虫（棘球）病是由棘球绦虫引起的人畜共患寄生虫病。我国西部是该病的高发区，在新疆其主要有2种病原体，即：囊型棘球蚴/细粒棘球绦虫，泡型棘球蚴/多房棘球绦虫。虽然对棘球蚴病及其成虫开展过大量的流行病学调查，但对广袤的天山山区，仍未就个别地理隔离区域进行过系统的棘球蚴/棘球绦虫病原学调查。新疆天山特-昭盆形成的昭苏草原就是由特克斯河冲击形成的高山盆地，紧邻哈萨克斯坦，地理隔离明显，尚未开展过该病原的系统调查。本研究就是通过形态学、病理学和分子生物学方法对该区域人畜共患棘球病动物源病原进行系统调查。采集病原样品，感染（原发/继发感染）实验动物，获得实验室感染病原体；明确该病原生存现状，变异程度，开展基因分型和系统进化分析；建立天山特-昭盆地棘球蚴实验鼠继发感染动物模型，以期活体保存该虫种。

Hydatid disease caused by echinococcus is considered as one of the most important zoonotic parasitic diseases.It is significantly high prevalence, 2 main types of pathogens, cystic echinococcosis/echinococcus granulosus , alveolar echinococcosis / echinococcus multilocularis in the west of China, Xinjiang. Although a large number of epidemiological studies of echinococcus and adults were carried out, there were no systematic investigations of the animal’s pathogen in the individual region of Tianshan mountains.The basin of Tekes and Zhaosu formed by the Tekes River impacting , adjacent to Kazakhstan, obviously geographic isolation, had not yet investigaed the echinococcus pathogen. This research aimed to use morphology, pathology and molecular biology methods to probe the animal’s pathogen of zoonotic echinococcus disease. Pathogen samples were collected, infected (primary/secondary) in laboratory animals,obtained available infected pathogens; evaluated the pathogen survival status and the variability level, identified genotypes and phylogenetic analysis; constructed the animal model of mice with secondary infected echinococcus and conserved the living species.