TOF-PET的应用研究对提高PET探测器模块的时间性能有着迫切需求。本课题在申请者已有的基于连续晶体PET探测器高位置分辨研究工作的基础上，提出开展连续晶体PET探测器高时间分辨技术的研究。课题将通过实验测试手段揭示PET探测器定时链上的各个环节对定时精度的影响，特别是γ光子作用位置对最终定时性能的影响，提出研究基于时间读出驱动的新型定时校正方法，开展定时校正实用电路研究、以及满足TOF-PET应用要求的高精度TDC技术研究，并和现有的神经网络三维定位算法以及TODT阳极信号读出新方法结合，面向实际应用，研发具有高位置分辨和高时间分辨能力的PET探测器模块原理样机，为基于这一新型探测器结构的高性能TOF-PET的研发做技术准备。

The development of TOF-PET has a very high demand to the timing performance of PET detectors. Based on our research results on high spatial resolution of continuous crystal PET detectors, we propose to study the timing techniques for its high temporal resolution. By experimental measurements, the project will unveil the effects to the timing accuracy coming from all the parts in the timing chain，including the influence from different interaction position of γ photon in detector. Then,the project will focus on a time readout driven timing correction solution to improve the timing performance, and study its practical electronics circuit as well as the high resolution TDC circuits for TOF-PET applications. Combining the new techniques for the continuous crystal based PET detector, such as neural network based position estimation, TODT anode readout scheme, and the timing techniques this project will have, the project will finally build a practical prototype of the PET detector module with a high spatial resolution and a high temporal resolution. The project is an essential technique preparation for the future development of high performance TOF-PET using this new type of detector structures.