水稻白叶枯病抗性基因Xa21抗性增强的分子机制

由革兰氏阴性菌黄单孢菌（Xanthomonas oryzae pv. oryzae，简称Xoo）引起的水稻白叶枯病是对水稻最具破坏性的病害之一。利用抗病基因培育抗病品种是控制白叶枯病最经济有效的方法。Xa21是水稻中克隆的第一个抗病基因，由于其对白叶枯病的广谱高抗性，自克隆后便受到很多关注。研究发现Xa21介导的抗病反应受水稻发育时期的影响，表现为成株期抗性。在前期的研究中，我们获得了一个Xa21转基因系DXT，接菌研究发现DXT对白叶枯病的抗性表现出全生育期的抗性，打破了Xa21抗性的发育调控性。本项目拟以DXT为材料，研究Xa21抗性改变的分子机理，研究成果对水稻的白叶枯病抗病育种具有重要的指导意义。

Bacterial leaf blight (BLB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the most devastating rice diseases in the world. Utilization of resistance genes in breeding programs has been the most effective and economical strategy for controlling bacterial blight.Xa21, the first-cloned BLB resistant gene from Oryza longistaminata, has received much attention because of its broad spectrum of resistance to BLB。The previous studies showed that Xa21-mediated resistance response was developmentally controled and plants carring Xa21 showed adult period resistance.In our prior research, we found a Xa21 transgenic line DXT which overcome the developmental controll of Xa21-mediated resistance response showed whole growth period resistance to BB.In this project, we aim to explore the molecular mechanism of whole growth period resistance to BB in DXT. The research results has important guiding significance to rice bacterial blight resistance breeding.