Anticoccidial Effect of Herbal Powder "Shi Ying Zi" in Chickens Infected with Eimeria tenella.
Anticoccidial Effect of Herbal Powder "Shi Ying Zi" in Chickens Infected with Eimeria tenella.
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DOI：
10.3390/ani10091484
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发表时间：
2020-08-24
期刊：
影响因子：
--
通讯作者：
Yin Z
中科院分区：
文献类型：
--
作者：
Song X;Li Y;Chen S;Jia R;Huang Y;Zou Y;Li L;Zhao X;Yin Z
草药在家禽疾病控制中发挥着越来越重要的作用。本研究表明，由蛇床子（Cnidium monnieri（L.）Cuss，蒲公英Taraxacum mongolicum Hand.马兹氯化钠可通过预防性或治疗性给药保护雏鸡免受柔嫩艾美耳球虫感染。“石樱子”散能提高球虫的存活率和相对生长率，其抗球虫指数分别为165（预防效果）和144（治疗效果），与阳性对照莫能菌素和磺胺吡嗪相当。“石樱子”散对大肠杆菌有一定的防治作用。tenella感染球虫病是影响养禽业最重要的经济疾病之一。目前兽医临床使用的抗球虫药物存在诸多不足，迫切需要新的控制措施。本研究以蛇床子为主要原料，研制了一种抗球虫中药散剂“石饮子”。Cuss，蒲公英Taraxacum mongolicum Hand.马兹和氯化钠。感染柔嫩艾美耳球虫的雏鸡，在感染前3d补食茵子散或在感染后给予食茵子散治疗，可提高雏鸡的存活率和相对生长率，减轻盲肠、肝脏和肾脏的病理变化。石饮子散能恢复血清谷丙转氨酶、肌酐、白蛋白、甘油三酯水平。出血发生率和粪便中卵囊总数减少。抗球虫指数为预防效果165，治疗效果144。抗球虫作用与阳性对照（莫能菌素和磺胺吡嗪）相同。结果表明，石樱子散具有较强的抗球虫作用，对大肠杆菌有一定的控制作用。tenella感染
Herbal medicines are playing an increasingly important role in the control of poultry diseases. The present study demonstrated that the herbal powder “Shi Ying Zi” consisting of Cnidium monnieri (L.) Cuss, Taraxacum mongolicum Hand.-Mazz., and sodium chloride could protect chickens from infection with Eimeria tenella through prophylactic or therapeutic administration. The “Shi Ying Zi” powder could improve the survival rate and relative growth rate with the anti-coccidial indexes of 165 (prophylactic effect) and 144 (therapeutic effect), which were equal to positive controls (monensin and sulfamlopyrazine). The “Shi Ying Zi” powder exhibits the potential to control E. tenella infection. Coccidiosis is one of the most economically important diseases affecting the poultry industry. Currently, anticoccidial drugs used in veterinary clinics show many deficiencies, and new control measures are urgently needed. This study presents an anticoccidial herbal powder “Shi Yin Zi”, which consists of Cnidium monnieri (L.) Cuss, Taraxacum mongolicum Hand.-Mazz., and sodium chloride. In chickens infected with Eimeria tenella, supplementation with “Shi Yin Zi” powder for 3 d prior to infection or treatment with “Shi Yin Zi” powder after infection could improve the survival rate and relative growth rate and alleviate the pathological changes in the cecum, liver, and kidney. “Shi Yin Zi” powder could recover the levels of alanine aminotransferase, creatinine, albumin, and triglycerides in serum. The hemorrhage occurrence and total number of oocysts in feces were reduced. The anti-coccidial indexes reached 165 for the prophylactic effect and 144 for the therapeutic effect. The anti-coccidial effects were equal to positive controls (monensin and sulfamlopyrazine). These results suggest that “Shi Ying Zi” powder possesses a potent anticoccidial effect and exhibits the potential to control E. tenella infection.
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影响因子：
3.6
作者：
Adams, C;Vahl, HA;Veldman, A
通讯作者：
Veldman, A
影响因子：
1.3
作者：
DUTTA, GP;MOHAN, A;TRIPATHI, R
通讯作者：
TRIPATHI, R
影响因子：
1.2
作者：
El-Abasy, M;Motobu, M;Hirota, Y
通讯作者：
Hirota, Y
影响因子：
2.8
作者：
KAWAZOE, U;DIFABIO, J
通讯作者：
DIFABIO, J
影响因子：
8.8
作者：
Liu KD;Thompson BT;Ancukiewicz M;Steingrub JS;Douglas IS;Matthay MA;Wright P;Peterson MW;Rock P;Hyzy RC;Anzueto A;Truwit JD;National Institutes of Health National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network
通讯作者：
National Institutes of Health National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network