Combined large cell neuroendocrine carcinoma with giant cell carcinoma of the lungs: a case report.

Combined large cell neuroendocrine carcinoma with giant cell carcinoma of the lungs: a case report.
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DOI:
10.1186/1477-7819-11-205
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发表时间:
2013-08-19
影响因子:
3.2
通讯作者:
Miyokawa N
Miyokawa N
中科院分区:
医学3区
文献类型:
--
作者:
Hayashi S;Kitada M;Ishibashi K;Matsuda Y;Miyokawa N

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合并肺大细胞神经内分泌癌(合并LCNEC)合并巨细胞癌极为罕见。一名65岁的男性被发现在他的左肺野有一个异常的阴影。CT显示左侧S9有一个2.8×2.2厘米的实性圆形肿块。患者接受了左下叶切除和纵隔淋巴结清扫术。组织病理学检查发现LCNEC,合并巨细胞癌。患者接受了S一号(TS-1,一种口服氟嘧啶)的化疗,已无病8个多月。LCNEC合并巨细胞癌是一种非常罕见且恶性潜能较高的肿瘤,建议采用多学科综合治疗和密切随访。
Combined large cell neuroendocrine carcinoma of the lungs (combined LCNEC) with giant cell carcinoma is extremely rare. A 65-year-old man was found to have an abnormal shadow in his left lung field. Computed tomography revealed a solid, round mass measuring 2.8 × 2.2 cm that was located in the left S9. The patient underwent left lower lobectomy and mediastinal lymph node dissection. Histopathological examination revealed an LCNEC, combined with giant cell carcinoma. The patient received by S-1 (TS-1, an oral fluoropyrimidine) chemotherapy, and he has been disease-free for over 8 months. Combined LCNEC with giant cell carcinoma is an extremely rare tumor with high malignant potential, and thus, multidisciplinary therapy and close follow-up are advised.
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发表时间: 2002-11-01
期刊: LUNG CANCER
影响因子: 5.3
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