Mouse ooplasm confers context-specific reprogramming capacity.
Mouse ooplasm confers context-specific reprogramming capacity.
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DOI:
10.1038/ng.2382
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发表时间:
2012-09
期刊:
影响因子:
30.8
通讯作者:
Meissner A
中科院分区:
文献类型:
--
作者:
Chan MM;Smith ZD;Egli D;Regev A;Meissner A
Enucleated oocytes have the remarkable ability to reprogram somatic nuclei back to totipotency. Here we investigate genome-scale DNA methylation patterns after nuclear transfer and compare them to the dynamics at fertilization. We identify specific targets for DNA demethylation after nuclear transfer such as germ-line associated promoters, as well as unique limitations that include certain repetitive element classes.
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影响因子:
64.8
作者:
Wakayama, T;Perry, ACF;Yanagimachi, R
通讯作者:
Yanagimachi, R
影响因子:
16.6
作者:
Egli, Dieter;Chen, Alice E.;Eggan, Kevin
通讯作者:
Eggan, Kevin
DOI:
10.1073/pnas.241522698
发表时间:
2001-11-20
影响因子:
11.1
作者:
Dean, W;Santos, F;Reik, W
通讯作者:
Reik, W
影响因子:
64.8
作者:
Meissner, Alexander;Mikkelsen, Tarjei S.;Gu, Hongcang;Wernig, Marius;Hanna, Jacob;Sivachenko, Andrey;Zhang, Xiaolan;Bernstein, Bradley E.;Nusbaum, Chad;Jaffe, David B.;Gnirke, Andreas;Jaenisch, Rudolf;Lander, Eric S.
通讯作者:
Lander, Eric S.
影响因子:
64.8
作者:
Smith, Zachary D.;Chan, Michelle M.;Mikkelsen, Tarjei S.;Gu, Hongcang;Gnirke, Andreas;Regev, Aviv;Meissner, Alexander
通讯作者:
Meissner, Alexander