Use of conjoint analysis to assess HIV vaccine acceptability: feasibility of an innovation in the assessment of consumer health-care preferences.

Use of conjoint analysis to assess HIV vaccine acceptability: feasibility of an innovation in the assessment of consumer health-care preferences.
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DOI:
10.1258/ijsa.2011.011189
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发表时间:
2012-04
影响因子:
1.4
通讯作者:
Duan N
Duan N
中科院分区:
医学4区
文献类型:
--
作者:
Lee SJ;Newman PA;Comulada WS;Cunningham WE;Duan N

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让消费者参与未来制定保健创新传播战略可能有助于确保可接受性。我们研究了在三个不同社区中使用联合分析来评估未来HIV疫苗可接受性的可行性:美国加利福尼亚州洛杉矶的多种族样本(n = 143);洛杉矶的泰国居民样本(三组,n = 27)和多伦多的原住民样本(n = 13)。在洛杉矶样本中,功效对可接受性的影响最大,其次是跨枝保护、副作用和保护时间;泰国-洛杉矶样本的副作用和保护时间;以及多伦多原住民样本的剂量和保护时间。联合分析提供了对未来艾滋病毒疫苗的不同最终用户的普遍和特定人群偏好的见解,对传播工作的循证目标有影响,以优化疫苗的吸收。
Engaging consumers in prospectively shaping strategies for dissemination of health-care innovations may help to ensure acceptability. We examined the feasibility of using conjoint analysis to assess future HIV vaccine acceptability among three diverse communities: a multiethnic sample in Los Angeles, CA, USA (n = 143); a Thai resident sample in Los Angeles (three groups; n = 27) and an Aboriginal peoples sample in Toronto (n = 13). Efficacy had the greatest impact on acceptability for all three groups, followed by cross-clade protection, side-effects and duration of protection in the Los Angeles sample; side-effects and duration of protection in the Thai-Los Angeles sample; and number of doses and duration of protection in the Aboriginal peoples-Toronto sample. Conjoint analysis provided insights into universal and population-specific preferences among diverse end users of future HIV vaccines, with implications for evidence-informed targeting of dissemination efforts to optimize vaccine uptake.
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