Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge.
Analysis of the genetic diversity and mRNA expression level in porcine reproductive and respiratory syndrome virus vaccinated pigs that developed short or long viremias after challenge.
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DOI:
10.1186/s13567-018-0514-1
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发表时间:
2018-02-15
影响因子:
4.4
通讯作者:
Darwich L
中科院分区:
文献类型:
--
作者:
Cortey M;Arocena G;Ait-Ali T;Vidal A;Li Y;Martín-Valls G;Wilson AD;Archibald AL;Mateu E;Darwich L
Porcine reproductive and respiratory syndrome virus (PRRSv) infection alters the host’s cellular and humoral immune response. Immunity against PRRSv is multigenic and vary between individuals. The aim of the present study was to compare several genes that encode for molecules involved in the immune response between two groups of vaccinated pigs that experienced short or long viremic periods after PRRSv challenge. These analyses include the sequencing of four SLA Class I, two Class II allele groups, and CD163, plus the analysis by quantitative realtime qRT-PCR of the constitutive expression of TLR2, TLR3, TLR4, TLR7, TLR8 and TLR9 mRNA and other molecules in peripheral blood mononuclear cells.
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DOI:
10.1186/1297-9686-46-18
发表时间:
2014-03-04
期刊:
Genetics, selection, evolution : GSE
影响因子:
--
作者:
Boddicker NJ;Bjorkquist A;Rowland RR;Lunney JK;Reecy JM;Dekkers JC
通讯作者:
Dekkers JC
影响因子:
2.8
作者:
Ren, Y. W.;Zhang, Y. Y.;Zhang, S. J.
通讯作者:
Zhang, S. J.
DOI:
10.1099/jgv.0.000859
发表时间:
2017-08
期刊:
The Journal of general virology
影响因子:
--
作者:
Xie J;Christiaens I;Yang B;Breedam WV;Cui T;Nauwynck HJ
通讯作者:
Nauwynck HJ
影响因子:
3.3
作者:
Pileri, E.;Gibert, E.;Mateu, E.
通讯作者:
Mateu, E.
影响因子:
--
作者:
Thong, L. Minh;Choi, H.;Park, C.
通讯作者:
Park, C.