Folic acid food fortification-its history, effect, concerns, and future directions.
Folic acid food fortification-its history, effect, concerns, and future directions.
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作者：
Crider KS;Bailey LB;Berry RJ
众所周知，妊娠期摄入叶酸可以降低孕妇生下患有神经管出生缺陷(NTD)的婴儿的风险。强制使用叶酸强化食品的国家计划降低了世界范围内NTDS的患病率。围绕可能出现的意想不到的后果的不确定性导致了人们对叶酸摄入量增加和食品强化计划的担忧。这种不确定性强调了持续监测防御工事方案的必要性，以准确衡量其效果以及在出现关切时解决这些问题的能力。该综述重点介绍了叶酸食品强化计划的历史、作用、关注和未来的发展方向。
Periconceptional intake of folic acid is known to reduce a woman’s risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended consequences has led to concerns about higher folic acid intake and food fortification programs. This uncertainty emphasizes the need to continually monitor fortification programs for accurate measures of their effect and the ability to address concerns as they arise. This review highlights the history, effect, concerns, and future directions of folic acid food fortification programs.
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影响因子：
2.8
作者：
Crozier, Sarah R.;Robinson, Sian M.;Inskip, Hazel M.
通讯作者：
Inskip, Hazel M.
DOI：
10.1002/bdra.20468
发表时间：
2008-07-01
影响因子：
--
作者：
Boulet, Sheree L.;Yang, Quanhe;Mulinare, Joe
通讯作者：
Mulinare, Joe
影响因子：
7.1
作者：
Bailey, Regan L.;Mills, James L.;Picciano, Mary Frances
通讯作者：
Picciano, Mary Frances
影响因子：
4.2
作者：
Berner, LA;Clydesdale, FM;Douglass, JS
通讯作者：
Douglass, JS
DOI：
10.1016/0140-6736(91)90133-a
发表时间：
1991-07-20
期刊：
Lancet (London, England)
影响因子：
--
作者：
通讯作者：
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