Use of the transbronchial biopsy for diagnosis of opportunistic pulmonary infections in acquired immunodeficiency syndrome (AIDS).
Use of the transbronchial biopsy for diagnosis of opportunistic pulmonary infections in acquired immunodeficiency syndrome (AIDS).
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使用经支气管活检诊断获得性免疫缺陷综合征（艾滋病）的机会性肺部感染。
DOI：
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发表时间：
1984
影响因子：
3.5
通讯作者：
W. Keith Hadley
中科院分区：
文献类型：
--
作者：
Walter Blumenfeld;Elizabeth Wagar;W. Keith Hadley
作者使用了一种方法，包括肺活检的吉姆萨染色触摸准备和相同活检的病毒和微生物培养。将这种细胞学方法的病原体诊断率与常规组织学方法同时进行的活组织检查的诊断率进行比较，并根据需要进行苏木精和伊红、银乌洛托品和其他染色。对38例具有获得性免疫缺陷综合征（AIDS）临床和实验室特征的男性患者进行了59例经支气管活检和8例开胸肺活检，以确定其肺部疾病的病因。16例确诊为卡氏肺孢子虫肺炎。当有足够的材料时，Giemsa染色的触摸准备与组织学检查一致。触摸准备标本培养，并与卡氏肺孢子虫的患者也有巨细胞病毒（CMV）。另外6例患者有肺部CMV感染，无卡氏肺孢子虫肺炎证据。在这6名患者中还发现了分枝杆菌和真菌感染。16例患者无特异性诊断。有了足够的材料，他们的方法提供了可靠的结果，并在两到三个小时内诊断卡氏肺孢子虫。此外，它节省了所需的标本量，因为相同的材料可用于培养。
The authors used a method that includes Giemsa-stained touch preparations of a lung biopsy and culture of the same biopsy for viruses and microorganisms. The yield of etiologic agent diagnoses by this cytologic method was compared with yield from a simultaneous biopsy processed by usual histologic methods and stained by hematoxylin and eosin, silver methenamine, and other stains as necessary. Fifty-nine transbronchial biopsies and eight open lung biopsies were processed on 38 male patients with the clinical and laboratory features of acquired immunodeficiency syndrome (AIDS) to determine the etiology of their pulmonary disease. Pneumocystis carinii pneumonia was diagnosed in 16 patients. When sufficient material was available, the Giemsa-stained touch preparation agreed with the histologic examination. The touch preparation specimens were cultured, and seven of the patients with Pneumocystis carinii also had cytomegalovirus (CMV). Six additional patients had pulmonary CMV infection without evidence of Pneumocystis carinii pneumonia. Mycobacterial and fungal infections also were identified in these six patients. Sixteen patients had no specific diagnosis. With adequate material, their method provides reliable results and diagnosis within two to three hours of Pneumocystis carinii. In addition, it conserves the amount of specimen required, since the same material can be used for culture.
影响因子：
39.2
作者：
MORRIS, L;DISTENFELD, A;KARPATKIN, S
通讯作者：
KARPATKIN, S
慢性浸润性肺疾病经支气管活检和开放活检的比较。
DOI：
10.1164/arrd.1981.123.3.280
发表时间：
1981
期刊：
The American review of respiratory disease
影响因子：
--
作者：
Wall,CP;Gaensler,EA;Carrington,CB;Hayes,JA
通讯作者：
Hayes,JA
通过开肺活检的接触印迹快速细胞学诊断巨细胞病毒间质性肺炎。
影响因子：
3.5
作者：
Shulman,HM;Hackman,RC;Sale,GE;Meyers,JD
通讯作者：
Meyers,JD