Eating for two: how metabolism establishes interspecies interactions in the gut.
Eating for two: how metabolism establishes interspecies interactions in the gut.
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DOI：
10.1016/j.chom.2011.10.002
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发表时间：
2011-10-20
影响因子：
30.3
通讯作者：
Sonnenburg JL
中科院分区：
文献类型：
--
作者：
Fischbach MA;Sonnenburg JL
在细菌群落中，“经济紧缩时期”是常态。在细菌谋生面临的众多挑战中，可能没有一项比产生能量、维持氧化还原平衡以及获取碳和氮来合成初级代谢物更重要。细菌应对这些挑战的能力在很大程度上取决于其群落的其余部分。事实上，细菌交流的最基本方式是输入新陈代谢的底物，并输出新陈代谢的最终产品。作为这一原理的一个例证，我们将沿着许多类杆菌属物种共同的碳水化合物分解代谢途径，强调在其关键步骤建立的(通常不可避免的)种间相互作用。我们还讨论了在维持宿主相关微生物群落稳定性方面的代谢因素。
In bacterial communities, ‘tight economic times’ are the norm. Of the many challenges bacteria face in making a living, perhaps none are more important than generating energy, maintaining redox balance, and acquiring carbon and nitrogen to synthesize primary metabolites. The ability of bacteria to meet these challenges depends heavily on the rest of their community. Indeed, the most fundamental way in which bacteria communicate is by importing the substrates for metabolism and exporting metabolic end products. As an illustration of this principle, we will travel down a carbohydrate catabolic pathway common to many species of Bacteroides, highlighting the interspecies interactions established (often inevitably) at its key steps. We also discuss the metabolic considerations in maintaining the stability of host-associated microbial communities.
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影响因子：
24.5
作者：
FINNIE, IA;DWARAKANATH, AD;RHODES, JM
通讯作者：
RHODES, JM
影响因子：
64.8
作者：
Arumugam, Manimozhiyan;Raes, Jeroen;Pelletier, Eric;Le Paslier, Denis;Yamada, Takuji;Mende, Daniel R.;Fernandes, Gabriel R.;Tap, Julien;Bruls, Thomas;Batto, Jean-Michel;Bertalan, Marcelo;Borruel, Natalia;Casellas, Francesc;Fernandez, Leyden;Gautier, Laurent;Hansen, Torben;Hattori, Masahira;Hayashi, Tetsuya;Kleerebezem, Michiel;Kurokawa, Ken;Leclerc, Marion;Levenez, Florence;Manichanh, Chaysavanh;Nielsen, H. Bjorn;Nielsen, Trine;Pons, Nicolas;Poulain, Julie;Qin, Junjie;Sicheritz-Ponten, Thomas;Tims, Sebastian;Torrents, David;Ugarte, Edgardo;Zoetendal, Erwin G.;Wang, Jun;Guarner, Francisco;Pedersen, Oluf;de Vos, Willem M.;Brunak, Soren;Dore, Joel;Weissenbach, Jean;Ehrlich, S. Dusko;Bork, Peer
通讯作者：
Bork, Peer
影响因子：
3.2
作者：
DEHORITY, BA
通讯作者：
DEHORITY, BA
影响因子：
2.1
作者：
Chassard, C;Bernalier-Donadille, A
通讯作者：
Bernalier-Donadille, A
DOI：
10.1080/07315724.2009.10719768
发表时间：
2009-04-01
影响因子：
3.5
作者：
Alvarez-Acosta, Thais;Leon, Cira;Colina-Chourio, Jose A.
通讯作者：
Colina-Chourio, Jose A.