Comparison of the amblyopia treatment study HOTV and the electronic-early treatment of diabetic retinopathy study visual acuity protocols in amblyopic children aged 5 to 11 years.

Comparison of the amblyopia treatment study HOTV and the electronic-early treatment of diabetic retinopathy study visual acuity protocols in amblyopic children aged 5 to 11 years.
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DOI:
10.1016/j.jaapos.2008.07.007
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发表时间:
2009-02
期刊:
影响因子:
1.6
通讯作者:
Holmes, Jonathan M.
Holmes, Jonathan M.
中科院分区:
医学4区
文献类型:
--
作者:
Birch, Eileen E.;Strauber, Samara F.;Beck, Roy W.;Holmes, Jonathan M.

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作为弱视治疗研究中弱视儿童长期随访的一部分,我们使用两种已建立的视力方案,即弱视治疗研究HOTV(ATS HOTV)视力方案和糖尿病视网膜病变电子早期治疗研究(E-ETDRS)方案,在每年的一次访视中测试了142例患者双眼的视力。试验时的平均年龄为9.0岁(范围= 5.6 - 11.9岁)。相对于E-ETDRS方案,ATS-HOTV方案导致视敏度的平均高估(弱视眼为0.68行;对侧眼为0.25行)。高估主要发生在E-ETDRS视力低于0.3 logMAR时。ATS-HOTV视力也低估了0.42行的眼间视力差异。当使用ATS-HOTV方案时,将“接近正常”的视力或眼间差异解释为“在正常范围内”时,谨慎可能是明智的,因为ATS-HOTV方法可能比E-ETDRS对弱视眼的表现有轻微的偏倚。
As part of the longterm follow-up of amblyopic children who were enrolled in the Amblyopia Treatment Study, we tested visual acuity in both eyes of 142 patients using two established visual acuity protocols, the Amblyopia Treatment Study HOTV (ATS HOTV) visual acuity protocol and the Electronic-Early Treatment of Diabetic Retinopathy Study (E-ETDRS) protocol, at one of the annual visits. Mean age at the time of testing was 9.0 years (range = 5.6 to 11.9 years). The ATS-HOTV protocol resulted in a slight mean overestimate of visual acuity relative to the E-ETDRS protocol (0.68 lines for amblyopic eyes; 0.25 lines for fellow eyes). The overestimation occurred primarily when the E-ETDRS visual acuity was poorer than 0.3 logMAR. ATS-HOTV acuity also underestimated interocular visual acuity differences by 0.42 lines. When using the ATS-HOTV protocol, it may be wise to exercise caution when interpreting “near normal” visual acuity or interocular differences as “within normal” because the ATS-HOTV method may have a slight bias toward better performance of amblyopic eyes than E-ETDRS.
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