Sex Steroids Mediate Bidirectional Interactions Between Hosts and Microbes.
Sex Steroids Mediate Bidirectional Interactions Between Hosts and Microbes.
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DOI：
10.1016/j.yhbeh.2016.10.016
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发表时间：
2017-03
影响因子：
3.5
通讯作者：
Klein SL
中科院分区：
文献类型：
--
作者：
Vom Steeg LG;Klein SL
The outcome of microbial infections in mammals, including humans, is affected by the age, sex, and reproductive status of the host suggesting a role for sex steroid hormones. Testosterone, estradiol, and progesterone, signaling through their respective steroid receptors, affect the functioning of immune cells to cause differential susceptibility to parasitic, bacterial, and viral infections. Microbes, including fungi, bacteria, parasites, and viruses, can also use sex steroid hormones and manipulate sex steroid receptor signaling mechanisms to increase their own survival and replication rate. The multifaceted use of sex steroid hormones by both microbes and hosts during infection forms the basis of this review. In the arms race between microbes and hosts, both hosts and microbes have evolved to utilize sex steroid hormone signaling mechanisms for survival.
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影响因子：
2.1
作者：
Botelho, M. C.;Crespo, M.;Correia da Costa, J. M.
通讯作者：
Correia da Costa, J. M.
影响因子：
3.6
作者：
BREIDBART, S;BURK, RD;SAENGER, P
通讯作者：
SAENGER, P
影响因子：
3.2
作者：
Antunes, L. Caetano M.;Andersen, Sarah K.;Finlay, B. Brett
通讯作者：
Finlay, B. Brett
DOI：
10.1007/978-3-642-02155-8_7
发表时间：
2010-01-01
期刊：
SEX HORMONES AND IMMUNITY TO INFECTION
影响因子：
--
作者：
Escobedo, Galileo;De Leon-Nava, Marco A.;Morales-Montor, Jorge
通讯作者：
Morales-Montor, Jorge
影响因子：
2.1
作者：
ELOISANTOS, S;OLSEN, NJ;COLLEY, DG
通讯作者：
COLLEY, DG