Online evaluation of novel choices by simultaneous representation of multiple memories.
Online evaluation of novel choices by simultaneous representation of multiple memories.
复制标题
DOI:
10.1038/nn.3515
复制
发表时间:
2013-10
影响因子:
25
通讯作者:
Behrens, Timothy E. J.
中科院分区:
文献类型:
--
作者:
Barron, Helen C.;Dolan, Raymond J.;Behrens, Timothy E. J.
Prior experience plays a critical role in decision making. It enables explicit representation of potential outcomes and provides training to valuation mechanisms. However, we can also make choices in the absence of prior experience, by merely imagining the consequences of a new experience. Here, using fMRI repetition suppression in humans, we show how neuronal representations of novel rewards can be constructed and evaluated. A likely novel experience is constructed by invoking multiple independent memories within hippocampus and medial prefrontal cortex. This construction persists for only a short time period, during which new associations are observed between the memories for component items. Together these findings suggest that in the absence of direct experience, co-activation of multiple relevant memories can provide a training signal to the valuation system which allows the consequences of new experiences to be imagined and acted upon.
登录
查看更多内容
DOI:
10.1523/jneurosci.4549-07.2007
发表时间:
2007-12-26
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Hassabis D;Kumaran D;Maguire EA
通讯作者:
Maguire EA
DOI:
10.1002/bs.3830090304
发表时间:
1964-01-01
期刊:
BEHAVIORAL SCIENCE
影响因子:
--
作者:
BECKER, GM;DEGROOT, MH;MARSCHAK, J
通讯作者:
MARSCHAK, J
影响因子:
16.2
作者:
Daw ND;Gershman SJ;Seymour B;Dayan P;Dolan RJ
通讯作者:
Dolan RJ
影响因子:
25
作者:
Kable, Joseph W.;Glimcher, Paul W.
通讯作者:
Glimcher, Paul W.
影响因子:
16.2
作者:
Boorman, Erie D.;Behrens, Timothy E. J.;Rushworth, Matthew F. S.
通讯作者:
Rushworth, Matthew F. S.