Everyday Impact of Cognitive Interventions in Mild Cognitive Impairment: a Systematic Review and Meta-Analysis.
Everyday Impact of Cognitive Interventions in Mild Cognitive Impairment: a Systematic Review and Meta-Analysis.
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DOI：
10.1007/s11065-016-9330-4
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发表时间：
2016-09
影响因子：
5.8
通讯作者：
Smith GE
中科院分区：
文献类型：
--
作者：
Chandler MJ;Parks AC;Marsiske M;Rotblatt LJ;Smith GE
认知干预在轻度认知障碍（MCI）寻求改善认知症状的条件。认知干预可能会也可能不会推广到日常生活的认知结果之外。本系统综述和荟萃分析旨在评估认知干预与MCI对照组相比对可推广结果测量的影响[日常生活活动（ADLs），情绪，生活质量（QOL）和元认知]，而不是单独的认知结果。遵循PRISMA准则。使用MEDLINE和PsychInfo作为数据源来定位与MCI个体认知干预相关的文献。认知干预研究需要纳入对照组或替代治疗对照组。30篇文章符合标准，包括6项计算机化认知干预，14项基于治疗师的干预和10项多模式（即认知干预加额外干预）研究。adl （d = 0.23）、情绪（d = 0.16）和元认知结局（d = 0.30）的总体中位效应较小，但显著，但生活质量（d = 0.10）没有。与对照组相比，计算机化研究似乎有利于情绪（抑郁、焦虑和冷漠），而基于治疗师的干预和多模式干预对adl和元认知结果的影响大于对照组。结果令人鼓舞，MCI的认知干预可能会影响日常生活，但还需要更多的研究。目前的综述和荟萃分析受限于我们仅使用PsychInfo和MEDLINE数据库，我们无法阅读非英文文章的全文，以及我们仅依赖已发表的数据来完成效应大小。
Cognitive interventions in Mild Cognitive Impairment (MCI) seek to ameliorate cognitive symptoms in the condition. Cognitive interventions may or may not generalize beyond cognitive outcomes to everyday life. This systematic review and meta-analysis sought to assess the effect of cognitive interventions compared to a control group in MCI on generalizability outcome measures [activities of daily living (ADLs), mood, quality of life (QOL), and metacognition] rather than cognitive outcomes alone. PRISMA guidelines were followed. MEDLINE and PsychInfo were utilized as data sources to locate references related to cognitive interventions in individuals with MCI. The cognitive intervention study was required to have a control or alternative treatment comparison group to be included. Thirty articles met criteria, including six computerized cognitive interventions, 14 therapist-based interventions, and 10 multimodal (i.e., cognitive intervention plus an additional intervention) studies. Small, but significant overall median effects were seen for ADLs (d = 0.23), mood (d = 0.16), and metacognitive outcomes (d = 0.30), but not for QOL (d = 0.10). Computerized studies appeared to benefit mood (depression, anxiety, and apathy) compared to controls, while therapist-based interventions and multimodal interventions had more impact on ADLs and metacognitive outcomes than control conditions. The results are encouraging that cognitive interventions in MCI may impact everyday life, but considerably more research is needed. The current review and meta-analysis is limited by our use of only PsychInfo and MEDLINE databases, our inability to read full text non-English articles, and our reliance on only published data to complete effect sizes.
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DOI：
10.1177/1533317513481093
发表时间：
2013-05-01
影响因子：
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作者：
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发表时间：
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