The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.
The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.
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DOI：
10.1016/j.jalz.2011.03.008
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发表时间：
2011-05
期刊：
影响因子：
--
通讯作者：
Phelps CH
中科院分区：
文献类型：
--
作者：
Albert MS;DeKosky ST;Dickson D;Dubois B;Feldman HH;Fox NC;Gamst A;Holtzman DM;Jagust WJ;Petersen RC;Snyder PJ;Carrillo MC;Thies B;Phelps CH
国家老龄化研究所和阿尔茨海默氏症协会委托一个研究小组负责制定阿尔茨海默氏症（AD）的症状性痴呆前期阶段的标准，在本文中称为AD引起的轻度认知障碍。该委员会制定了以下两套标准：（1）核心临床标准，可由医疗保健提供者使用，无需使用先进的成像技术或脑脊液分析，（2）研究标准，可用于临床研究环境，包括临床试验。第二组标准包括使用基于成像和脑脊液测量的生物标志物。AD所致轻度认知障碍的最终标准有四个确定性水平，这取决于生物标志物发现的存在和性质。需要做大量的工作来验证使用生物标志物的标准，并将生物标志物分析标准化，以用于社区环境。
The National Institute on Aging and the Alzheimer’s Association charged a workgroup with the task of developing criteria for the symptomatic predementia phase of Alzheimer’s disease (AD), referred to in this article as mild cognitive impairment due to AD. The workgroup developed the following two sets of criteria: (1) core clinical criteria that could be used by healthcare providers without access to advanced imaging techniques or cerebrospinal fluid analysis, and (2) research criteria that could be used in clinical research settings, including clinical trials. The second set of criteria incorporate the use of biomarkers based on imaging and cerebrospinal fluid measures. The final set of criteria for mild cognitive impairment due to AD has four levels of certainty, depending on the presence and nature of the biomarker findings. Considerable work is needed to validate the criteria that use biomarkers and to standardize biomarker analysis for use in community settings.
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DOI：
10.1016/j.jalz.2011.03.005
发表时间：
2011-05
期刊：
Alzheimer's & dementia : the journal of the Alzheimer's Association
影响因子：
--
作者：
McKhann GM;Knopman DS;Chertkow H;Hyman BT;Jack CR Jr;Kawas CH;Klunk WE;Koroshetz WJ;Manly JJ;Mayeux R;Mohs RC;Morris JC;Rossor MN;Scheltens P;Carrillo MC;Thies B;Weintraub S;Phelps CH
通讯作者：
Phelps CH
DOI：
10.1016/j.jalz.2011.03.004
发表时间：
2011-05
期刊：
Alzheimer's & dementia : the journal of the Alzheimer's Association
影响因子：
--
作者：
Jack CR Jr;Albert MS;Knopman DS;McKhann GM;Sperling RA;Carrillo MC;Thies B;Phelps CH
通讯作者：
Phelps CH
影响因子：
9.9
作者：
Bennett, DA;Schneider, JA;Wilson, RS
通讯作者：
Wilson, RS
影响因子：
11.1
作者：
Winblad, B;Palmer, K;Petersen, RC
通讯作者：
Petersen, RC
影响因子：
11.1
作者：
Petersen, RC
通讯作者：
Petersen, RC