Neutrophil Functional Heterogeneity and Implications for Viral Infections and Treatments.
Neutrophil Functional Heterogeneity and Implications for Viral Infections and Treatments.
复制标题
神经元功能异质性及其对病毒感染和治疗的意义。
DOI：
10.3390/cells11081322
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发表时间：
2022-04-13
期刊：
影响因子：
6
通讯作者：
Karimi, Khalil
中科院分区：
文献类型：
--
作者：
Chan, Lily;Morovati, Solmaz;Karimi, Negar;Alizadeh, Kasra;Vanderkamp, Sierra;Kakish, Julia E.;Bridle, Byram W.;Karimi, Khalil
Evidence suggests that neutrophils exert specialized effector functions during infection and inflammation, and that these cells can affect the duration, severity, and outcome of the infection. These functions are related to variations in phenotypes that have implications in immunoregulation during viral infections. Although the complexity of the heterogeneity of neutrophils is still in the process of being uncovered, evidence indicates that they display phenotypes and functions that can assist in viral clearance or augment and amplify the immunopathology of viruses. Therefore, deciphering and understanding neutrophil subsets and their polarization in viral infections is of importance. In this review, the different phenotypes of neutrophils and the roles they play in viral infections are discussed. We also examine the possible ways to target neutrophil subsets during viral infections as potential anti-viral treatments.
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DOI：
10.1084/jem.186.5.739
发表时间：
1997-08-29
期刊：
The Journal of experimental medicine
影响因子：
--
作者：
Chertov O;Ueda H;Xu LL;Tani K;Murphy WJ;Wang JM;Howard OM;Sayers TJ;Oppenheim JJ
通讯作者：
Oppenheim JJ
DOI：
10.4049/jimmunol.1002456
发表时间：
2010-11-01
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Cheung DS;Ehlenbach SJ;Kitchens RT;Riley DA;Thomas LL;Holtzman MJ;Grayson MH
通讯作者：
Grayson MH
影响因子：
6
作者：
Brazil, Jennifer C.;Sumagin, Ronen;Parkos, Charles A.
通讯作者：
Parkos, Charles A.
影响因子：
4.4
作者：
Almand, B;Clark, JI;Gabrilovich, DI
通讯作者：
Gabrilovich, DI
影响因子：
14.2
作者：
Cheung, Dorothy S.;Sigua, Jerome A.;Grayson, Mitchell H.
通讯作者：
Grayson, Mitchell H.