Surveillance in hospitalized children with infectious diseases in Japan: Pre- and post-coronavirus disease 2019.

Surveillance in hospitalized children with infectious diseases in Japan: Pre- and post-coronavirus disease 2019.
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DOI:
10.1016/j.jiac.2021.07.024
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发表时间:
2021-11
期刊:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
影响因子:
--
通讯作者:
Kawasaki Y
Kawasaki Y
中科院分区:
其他
文献类型:
--
作者:
Fukuda Y;Tsugawa T;Nagaoka Y;Ishii A;Nawa T;Togashi A;Kunizaki J;Hirakawa S;Iida J;Tanaka T;Kizawa T;Yamamoto D;Takeuchi R;Sakai Y;Kikuchi M;Nagai K;Asakura H;Tanaka R;Yoshida M;Hamada R;Kawasaki Y

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2019冠状病毒病(COVID-19)疫情在全球范围内迅速蔓延,各种感染控制措施对许多传染病的传播有重大影响。但是,目前还没有针对新冠肺炎疫情前后各种传染病住院儿童人数变化的多中心研究。我们于2019年7月至2021年2月对日本北海道县18家医院的住院儿科患者进行了一项多中心前瞻性调查。我们将2019年7月至2020年2月定义为covid -19前,将2020年7月至2021年2月定义为covid -19后。我们按性别和年龄调查了各种传染病。在研究期间,总共有5300名患者住院。新冠肺炎患者从前4266人减少到后701人(16.4%)。流感和RSV患者从covid -19前的308例减少到795例,covid -19后的0例和3例(0.4%)。然而,腺病毒(呼吸道感染)患者仅下降到covid前水平的60.9%(46-28)。轮状病毒、诺如病毒和腺病毒胃肠炎患者在covid -19后明显下降,分别为2.6%(38-1)、27.8%(97-27)和13.5%(37-5)。两个时期的尿路感染患者数量相似(109例和90例)。新冠肺炎后KD患者下降至31.7%(161-51)。建议戴口罩、勤洗手、酒精消毒等当前防控新冠肺炎的措施对各种传染病都是有效的。然而,这些影响因疾病而异。
The epidemic of coronavirus disease 2019 (COVID-19) rapidly spread worldwide, and the various infection control measures have a significant influence on the spread of many infectious diseases. However, there have been no multicenter studies on how the number of hospitalized children with various infectious diseases changed before and after the outbreak of COVID-19 in Japan. We conducted a multicenter, prospective survey for hospitalized pediatric patients in 18 hospitals in Hokkaido Prefecture, Japan, from July 2019 to February 2021. We defined July 2019 to February 2020 as pre-COVID-19, and July 2020 to February 2021 as post-COVID-19. We surveyed various infectious diseases by sex and age. In total, 5300 patients were hospitalized during the study period. The number of patients decreased from 4266 in the pre-COVID-19 period to 701 (16.4%) post-COVID-19. Patients with influenza and RSV decreased from 308 to 795 pre-COVID-19 to zero and three (0.4%) post-COVID-19. However, patients with adenovirus (respiratory infection) only decreased to 60.9% (46–28) of pre-COVID levels. Patients with rotavirus, norovirus, and adenovirus gastroenteritis decreased markedly post-COVID-19 to 2.6% (38–1), 27.8% (97–27) and 13.5% (37–5). The number of patients with UTIs was similar across the two periods (109 and 90). KD patients decreased to 31.7% (161–51) post-COVID-19. We suggest that current infection control measures for COVID-19 such as wearing masks, washing hands, and disinfecting hands with alcohol are effective against various infectious diseases. However, these effects vary by disease.
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