Convergent transcriptional specializations in the brains of humans and song-learning birds.
Convergent transcriptional specializations in the brains of humans and song-learning birds.
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DOI：
10.1126/science.1256846
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发表时间：
2014-12-12
期刊：
影响因子：
--
通讯作者：
Jarvis ED
中科院分区：
文献类型：
--
作者：
Pfenning AR;Hara E;Whitney O;Rivas MV;Wang R;Roulhac PL;Howard JT;Wirthlin M;Lovell PV;Ganapathy G;Mouncastle J;Moseley MA;Thompson JW;Soderblom EJ;Iriki A;Kato M;Gilbert MT;Zhang G;Bakken T;Bongaarts A;Bernard A;Lein E;Mello CV;Hartemink AJ;Jarvis ED
Song-learning birds and humans share independently evolved similarities in brain pathways for vocal learning that are essential for song and speech and are not found in most other species. Comparisons of brain transcriptomes of song-learning birds and humans relative to vocal nonlearners identified convergent gene expression specializations in specific song and speech brain regions of avian vocal learners and humans. The strongest shared profiles relate bird motor and striatal song-learning nuclei, respectively, with human laryngeal motor cortex and parts of the striatum that control speech production and learning. Most of the associated genes function in motor control and brain connectivity. Thus, convergent behavior and neural connectivity for a complex trait are associated with convergent specialized expression of multiple genes.
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影响因子：
3.7
作者：
Feenders, Gesa;Liedvogel, Miriam;Rivas, Miriam;Zapka, Manuela;Horita, Haruhito;Hara, Erina;Wada, Kazuhiro;Mouritsen, Henrik;Jarvis, Erich D.
通讯作者：
Jarvis, Erich D.
DOI：
10.1073/pnas.1201898109
发表时间：
2012-06-26
影响因子：
11.1
作者：
Barrett, H. Clark
通讯作者：
Barrett, H. Clark
影响因子：
2.5
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影响因子：
2.5
作者：
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通讯作者：
Jarvis, Erich D.
影响因子：
4.8
作者：
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通讯作者：
Sato, Marc