A case report of a deep surgical site infection with Terrisporobacter glycolicus/T. Mayombei and review of the literature.
A case report of a deep surgical site infection with Terrisporobacter glycolicus/T. Mayombei and review of the literature.
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DOI：
10.1186/s12879-016-1865-8
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发表时间：
2016-09-29
影响因子：
3.7
通讯作者：
Yansouni CP
中科院分区：
文献类型：
--
作者：
Cheng MP;Domingo MC;Lévesque S;Yansouni CP
有越来越多的数据关于Terrisporaculum glycolicus作为一种新兴的厌氧病原体。然而，迄今为止发表的少数病例通常将其报告为多微生物感染的一部分。在这里，我们描述了第一个报告的单一微生物手术部位感染这种细菌。鉴定方法，分类，和临床管理这种罕见的病原体进行了讨论。一名以前健康的66岁男子在创伤后左臂开放性鹰嘴骨折。他随后接受了切开复位内固定（ORIF），插入了鹰嘴锁定钢板和两枚锁定螺钉。术后10天，患者手术部位疼痛加剧，并发现伤口有绿色分泌物。伤口分泌物的培养物产生了经RapidANA®微生物鉴定系统鉴定为C的纯革兰氏阳性厌氧菌。艰难梭菌（特征000010，99.1%概率）。参考实验室检测将分离株鉴定为T。通过16 S rRNA基因测序鉴定为Clostridium glycolicus/mayombei（先前命名为Clostridium glycolicum/mayombei），通过MALDI-TOF质谱鉴定为Clostridium glycolicum。患者接受了为期8周的利福沙星和甲硝唑疗程，在12个月的随访中临床反应良好。我们描述的情况下，深部手术部位感染与T。在一些实施方案中，本发明涉及一种新的酵母菌，其包括Glycolicus/mayombei（以前分别称为Glycolicum和Clostridium mayombei），这扩展了我们对该病原体的临床谱的认识。该分离株被表型鉴定方法错误鉴定。
There are increasing data regarding Terrisporobacter glycolicus as an emerging anaerobic pathogen. However, the few published cases to date usually report it as part of a polymicrobial infection. Here, we describe the first reported monomicrobial surgical site infection with this bacterium. Identification methods, taxonomy, and clinical management of this rarely identified pathogen are also discussed. A previously healthy 66-year-old sustained an open olecranon fracture of his left arm after trauma. He subsequently underwent open reduction and internal fixation (ORIF), with insertion of an olecranon locking plate and two locking screws. Ten days after surgery, the patient developed increasing pain at the surgical site and noted green discharge from the wound. Culture of the wound discharge yielded grew a pure Gram-positive anaerobe identified by the RapidANA® microbial identification system as C. difficile (profile 000010, 99.1 % probability). Reference laboratory testing identified the isolate as T. glycolicus/mayombei (previously designated as Clostridium glycolicum/mayombei) by 16S rRNA gene sequencing and as Clostridium glycolicum by MALDI-TOF mass spectrometry. The patient received an 8-week course of moxifloxacin and metronidazole with an excellent clinical response at 12 months’ follow-up. We describe the case of a deep surgical site infection with T. glycolicus/mayombei (formerly known as Clostridium glycolicum and Clostridium mayombei, respectively), which extends our knowledge of the clinical spectrum of this pathogen. The isolate was misidentified by phenotypic identification methods.
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影响因子：
5.2
作者：
Malincarne, L;Ghebregzabher, M;Baldelli, F
通讯作者：
Baldelli, F
影响因子：
9.4
作者：
Jiang, Wei;Abrar, Sahibzada;Carroll, Karen C.
通讯作者：
Carroll, Karen C.
影响因子：
9.4
作者：
Elsayed, Sameer;Zhang, Kunyan
通讯作者：
Zhang, Kunyan
DOI：
10.1097/00005373-198408000-00009
发表时间：
1984-01-01
影响因子：
--
作者：
GUSTILO, RB;MENDOZA, RM;WILLIAMS, DN
通讯作者：
WILLIAMS, DN
DOI：
10.1099/ijs.0.059543-0
发表时间：
2014-05-01
影响因子：
2.8
作者：
Gerritsen, Jacoline;Fuentes, Susana;Smidt, Hauke
通讯作者：
Smidt, Hauke