Impact of stress on cancer metastasis.

Impact of stress on cancer metastasis.
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DOI:
10.2217/fon.10.142
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发表时间:
2010-12
期刊:
Future oncology (London, England)
影响因子:
--
通讯作者:
Sood AK
Sood AK
中科院分区:
其他
文献类型:
--
作者:
Moreno-Smith M;Lutgendorf SK;Sood AK

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The influence of psychosocial factors on the development and progression of cancer has been a longstanding hypothesis since ancient times. In fact, epidemiological and clinical studies over the past 30 years have provided strong evidence for links between chronic stress, depression and social isolation and cancer progression. By contrast, there is only limited evidence for the role of these behavioral factors in cancer initiation. Recent cellular and molecular studies have identified specific signaling pathways that impact cancer growth and metastasis. This article provides an overview of the relationship between psychosocial factors, specifically chronic stress, and cancer progression.
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