N100 cortical potentials accompanying disrupted auditory nerve activity in auditory neuropathy (AN): effects of signal intensity and continuous noise.
N100 cortical potentials accompanying disrupted auditory nerve activity in auditory neuropathy (AN): effects of signal intensity and continuous noise.
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DOI：
10.1016/j.clinph.2009.05.013
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发表时间：
2009-07
期刊：
影响因子：
--
通讯作者：
Dimitrijevic A
中科院分区：
文献类型：
--
作者：
Michalewski HJ;Starr A;Zeng FG;Dimitrijevic A
听觉神经病（AN）在安静时的听觉时间过程受损，类似于在噪声中测试的正常听力受试者。在安静和噪声条件下，分别测定了AN受试者在不同音调强度下的N100潜伏期，并与听力正常者进行了比较。受试者在安静和连续噪声（90 dB SPL）中接受简短的100 ms音调（1.0 kHz 100 dB至40 dB SPL）测试。N100潜伏期和振幅作为信号强度和可听度的函数进行分析。与正常组相比，安静时AN的N100潜伏期延迟，振幅降低;潜伏期延迟的程度与间隙检测阈值和语音识别评分的心理声学测量有关，但与可听度无关。在正常听力受试者的噪音伴随着N100潜伏期延迟和振幅减少平行于AN测试中发现的安静。额外的N100潜伏期延迟和振幅降低发生在AN与噪声。在AN受试者中，N100潜伏期与听觉时间任务的表现相关。噪声掩蔽在正常听力受试者影响N100潜伏期类似于AN在安静。N100潜伏期可以作为听觉时间过程效率的一个客观指标。
Auditory temporal processes in quiet are impaired in Auditory Neuropathy (AN) similar to normal hearing subjects tested in noise. N100 latencies were measured from AN subjects at several tone intensities in quiet and noise for comparison with a group of normal hearing individuals. Subjects were tested with brief 100 ms tones (1.0 kHz 100 dB to 40 dB SPL) in quiet and in continuous noise (90 dB SPL). N100 latency and amplitude were analyzed as a function of signal intensity and audibility. N100 latency in AN in quiet was delayed and amplitude was reduced compared to the normal group; the extent of latency delay was related to psychoacoustic measures of gap detection threshold and speech recognition scores, but not to audibility. Noise in normal hearing subjects was accompanied by N100 latency delays and amplitude reductions paralleling those found in AN tested in quiet. Additional N100 latency delays and amplitude reductions occurred in AN with noise. N100 latency to tones and performance on auditory temporal tasks were related in AN subjects. Noise masking in normal hearing subjects affected N100 latency to resemble AN in quiet. N100 latency to tones may serve as an objective measure of the efficiency of auditory temporal processes.
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影响因子：
4.7
作者：
Michalewski, HJ;Starr, A;Zeng, FG
通讯作者：
Zeng, FG
DOI：
10.1016/0013-4694(66)90039-3
发表时间：
1966-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
RAPIN, I;SCHIMMEL, H;POLLAK, C
通讯作者：
POLLAK, C
影响因子：
3.9
作者：
Rodriguez-Ballesteros, Montserrat;Reynoso, Raul;del Castillo, Ignacio
通讯作者：
del Castillo, Ignacio
影响因子：
64.8
作者：
POWERS, NL;SALVI, RJ;QIU, CX
通讯作者：
QIU, CX
影响因子：
2.6
作者：
Bahmad, Fayez, Jr.;Merchant, Saumil N.;Tranebjaerg, Lisbeth
通讯作者：
Tranebjaerg, Lisbeth