The relationship between tobacco smoke & bronchial asthma.

The relationship between tobacco smoke & bronchial asthma.
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与烟草烟雾的关系

DOI:
--
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发表时间:
2004
期刊:
The Indian journal of medical research
影响因子:
--
通讯作者:
D. Gupta
D. Gupta
中科院分区:
--
文献类型:
--
作者:
Sushil Jindal;D. Gupta

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支气管哮喘是一种常见病,是儿童和成人发病的重要原因。吸烟,包括主动吸烟和被动吸烟,即暴露于环境烟草烟雾(ETS)对哮喘有重要影响。成人吸烟可引起支气管刺激,诱发急性发作。它还会增加支气管的反应性,并引起呼吸道对几种职业性过敏原的致敏。吸烟也可能增加疾病的严重程度。成年哮喘患者持续吸烟可能导致气道阻塞的不可逆性和慢性阻塞性肺疾病的发展。暴露于ETS也以类似的方式影响哮喘。父母吸烟通常与儿童哮喘症状增加、呼吸道感染、急性发作和频繁住院有关。支气管反应性和气道敏化也可能增加。儿童时期接触吸烟也被认为是患哮喘的一个危险因素。同样,在子宫内暴露于母亲吸烟可能是早期发作哮喘的独立原因。成年哮喘患者因配偶、兄弟姐妹或同事吸烟而暴露于ETS同样令人烦恼。发病率增加,哮喘控制较差。减少ETS暴露后,哮喘症状急剧下降。
Bronchial asthma is a common disease and an important cause of morbidity among both children and adults. Tobacco smoking, both active and passive i.e., exposure to environmental tobacco smoke (ETS) has got important effects on asthma. Smoking by adults causes bronchial irritation and precipitates acute episodes. It also increases bronchial responsiveness and causes airway sensitization to several occupational allergens. Smoking may also increase the disease severity. Continued smoking by adult asthmatics is the likely cause of irreversibility of airway obstruction and development of chronic obstructive pulmonary disease. ETS exposure affects asthma in a similar fashion. Parental smoking is commonly associated with increased asthma symptoms, respiratory infections, acute episodes and frequent hospitalization of children. Bronchial responsiveness and airway sensitization may also increase. Childhood exposure to smoking is also considered as a risk factor for the development of asthma. Similarly, in utero exposure to maternal smoking may be independently responsible for early onset asthma. ETS exposure in adult asthmatics from smoking by spouses, siblings or colleagues is equally troublesome. There is increased morbidity and poorer asthma control. Asthmatic symptoms sharply decline after the ETS exposure is reduced.
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